Results 151 to 160 of about 2,169,697 (309)

Primitive hepatic venous plexus in a child with scimitar syndrome and pulmonary sequestration [PDF]

open access: yes, 2013
This article reports a case of scimitar syndrome with pulmonary sequestration, persistent primitive hepatic venous plexus and stenosis of the inferior vena cava in a child presenting with failure to thrive.
Morrison, M.L.   +2 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

ADAPTING INTERVENTIONS FOR SUSTAINABLE IMPLEMENTATION IN NEW CONTEXTS: CONSIDERATIONS FROM A STUDY ON ENHANCING COLLABORATION BETWEEN PSYCHIATRIC CARE AND OCCUPATIONAL HEALTH SPECIALISTS [PDF]

open access: yesPsychiatria Fennica
Background: The Coordinated Return to Work model, originally developed for an orthopaedic context, has been adapted for use in mental health settings.
MIKKO HENRIKSSON, PIRJO JUVONEN-POSTI, MARIANNA VIRTANEN, CHRISTINA TIKKA, TUULA OKSANEN
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Complex Percutaneous Coronary Intervention

open access: yes
This thesis contains 17 chapters about two major subjects. Part I focuses on the effects of chronic total occlusion percutaneous coronary intervention (CTO PCI) on myocardial ischemia reduction measured by [15O]H2O positron emission tomography (PET) perfusion imaging, on myocardial functional recovery measured by cardiac magnetic resonance imaging, on ...
openaire   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Complex coronary intervention [PDF]

open access: yesInterventional Cardiology Clinics, 2016
openaire   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

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