Full-Length P2X7 Structures Reveal How Palmitoylation Prevents Channel Desensitization.
Cell, 2019 P2X receptors are trimeric, non-selective cation channels activated by extracellular ATP. The P2X7 receptor subtype is a pharmacological target because of involvement in apoptotic, inflammatory, and tumor progression pathways. It is the most structurally
A. McCarthy, C. Yoshioka, S. E. Mansoor
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Complex length of short curves and Minimal Fibrations of hyperbolic three‐Manifolds fibering over the circle [PDF]
Proceedings of the London Mathematical Society, 2015 We investigate the maximal solid tubes around short simple closed geodesics in hyperbolic three‐manifolds and how the complex length of curves relates to closed least area incompressible minimal surfaces. As applications, we prove the existence of closed
Zheng Huang, Biao Wang
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Length, protein–protein interactions, and complexity [PDF]
Physica A: Statistical Mechanics and its Applications, 2005 13 pages, 5 figures, 2 tables, to appear in Physica ...
Tan, T. +3 more
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Modeling of long length and complex shaped chain and planed conveyor noise forming [PDF]
E3S Web of Conferences, 2020 The article presents an analysis of the chain-slat conveyor in terms of noise generation. It is shown that, due to the volumetric layout and long length, it is one of the main sources of noise generation.
Balinskaya Mariya +2 more
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Least-to-Most Prompting Enables Complex Reasoning in Large Language Models [PDF]
International Conference on Learning Representations, 2022 Chain-of-thought prompting has demonstrated remarkable performance on various natural language reasoning tasks. However, it tends to perform poorly on tasks which requires solving problems harder than the exemplars shown in the prompts.
Denny Zhou +9 more
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Sexual dimorphism of synaptonemal complex length in threespine stickleback fish
bioRxiv, 2020 Crossover frequency often differs substantially between sexes (i.e. heterochiasmy). Although this phenomenon is widespread throughout taxa, the mechanisms that lead to heterochiasmy remain unclear.
Barquiesha Madison +3 more
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Full-length synaptonemal complex grows continuously during meiotic prophase in budding yeast. [PDF]
PLoS Genetics, 2012 the synaptonemal complex (SC) links two meiotic prophase chromosomal events: homolog pairing and crossover recombination. SC formation involves the multimeric assembly of coiled-coil proteins (Zip1 in budding yeast) at the interface of aligned homologous
Karen Voelkel-Meiman +4 more
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Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
Science, 2020 How SARS-CoV-2 binds to human cells Scientists are racing to learn the secrets of severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), which is the cause of the pandemic disease COVID-19. The first step in viral entry is the binding of the viral
R. Yan +5 more
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Structures of full-length glycoprotein hormone receptor signaling complexes [PDF]
Nature, 2021 Luteinizing hormone (LH) and chorionic gonadotropin (CG) are members of the glycoprotein hormone family essential to human reproduction and are important therapeutic drugs. They activate the same G protein-coupled receptor, LHCGR, by binding to the large extracellular domain (ECD).
Jia Duan +15 more
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Physical complexity of variable length symbolic sequences [PDF]
Physica A: Statistical Mechanics and its Applications, 2011 8 pages, 7 figures ...
Briscoe, Gerard, De Wilde, Philippe
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