Results 71 to 80 of about 1,024,610 (314)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Levy random walks on multiplex networks [PDF]

open access: yes, 2016
Random walks constitute a fundamental mechanism for many dynamics taking place on complex networks. Besides, as a more realistic description of our society, multiplex networks have been receiving a growing interest, as well as the dynamical processes ...
Guo, Q.   +7 more
core   +1 more source

Malleability of complex networks [PDF]

open access: yesJournal of Statistical Mechanics: Theory and Experiment, 2019
Abstract Most complex networks are not static, but evolve along time. Given a specific configuration of one such changing network, it becomes a particularly interesting issue to quantify the diversity of possible unfoldings of its topology. In this work, we suggest the concept of malleability
Filipi Nascimento Silva   +2 more
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Distance Between Players During a Soccer Match: The Influence of Player Position

open access: yesFrontiers in Psychology, 2021
In this study, we analyse the proximity between professional players during a soccer match. Specifically, we are concerned about the time a player remains at a distance to a rival that is closer than 2 m, which has a series of consequences, from the risk
David Garrido   +7 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A new Zymomonas mobilis platform strain for the efficient production of chemicals

open access: yesMicrobial Cell Factories
Background Zymomonas mobilis is well known for its outstanding ability to produce ethanol with both high specific productivity and with high yield close to the theoretical maximum.
Jonas Frohwitter   +3 more
doaj   +1 more source

The Effects of Mindfulness on Brain Network Dynamics Following an Acute Stressor in a Population of Drinking Adults

open access: yesBrain Sciences
Background: Previous research has found that mindfulness-based techniques are beneficial for reducing stress in heavy-drinking individuals. However, the underlying neurobiology of these stress-reducing effects are unclear.
Shannon M. O’Donnell   +6 more
doaj   +1 more source

ENTIRETY — sEmanNTIc pRovisioning and govErning ioT devices in smart energY domain

open access: yesSoftwareX, 2022
ENTIRETY is an open-source web application that provides consistency for the devices in IoT platforms with a simple and unified way of governing and provisioning.
Maliheh Haghgoo   +3 more
doaj   +1 more source

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