Results 81 to 90 of about 3,130,788 (278)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
ENTIRETY — sEmanNTIc pRovisioning and govErning ioT devices in smart energY domain
SoftwareX, 2022 ENTIRETY is an open-source web application that provides consistency for the devices in IoT platforms with a simple and unified way of governing and provisioning.
Maliheh Haghgoo +3 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Structure of the Region-Technology Network as a Driver for Technological Innovation
Frontiers in Big Data, 2021 Agglomeration and spillovers are key phenomena of technological innovation, driving regional economic growth. Here, we investigate these phenomena through technological outputs of over 4,000 regions spanning 42 countries, by analyzing more than 30 years ...
Dion R. J. O’Neale +4 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
A new Zymomonas mobilis platform strain for the efficient production of chemicals
Microbial Cell FactoriesBackground Zymomonas mobilis is well known for its outstanding ability to produce ethanol with both high specific productivity and with high yield close to the theoretical maximum.
Jonas Frohwitter +3 more
doaj +1 more source
Brain SciencesBackground: Previous research has found that mindfulness-based techniques are beneficial for reducing stress in heavy-drinking individuals. However, the underlying neurobiology of these stress-reducing effects are unclear.
Shannon M. O’Donnell +6 more
doaj +1 more source
Role models for complex networks [PDF]
, 1999 We present a framework for automatically decomposing ("block-modeling") the functional classes of agents within a complex network. These classes are represented by the nodes of an image graph ("block model") depicting the main patterns of connectivity ...
Franx, M +3 more
core +6 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Sustainable growth in complex networks
, 2010 Based on the empirical analysis of the dependency network in 18 Java projects, we develop a novel model of network growth which considers both: an attachment mechanism and the addition of new nodes with a heterogeneous distribution of their initial ...
C. J. Tessone +8 more
core +1 more source