Results 101 to 110 of about 1,032,211 (315)

Infection spreading, detection and control in community networks [PDF]

open access: yes, 2017
Community structures widely exist in various complex networks. Extensive studies have been carried out on defining and quantifying community structures as well as developing algorithms for detecting them in extra-large complex systems.
Xiao, Gaoxi, Yu, Yi
core   +1 more source

Sensitivity of Complex Networks

open access: yesCoRR, 2016
The sensitivity (i.e. dynamic response) of complex networked systems has not been well understood, making difficult to predict whether new macroscopic dynamic behavior will emerge even if we know exactly how individual nodes behave and how they are coupled.
Marco Tulio Angulo   +3 more
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Characteristics of Biological Networks [PDF]

open access: yes, 2004
Network principles describe uniformly systems as diverse as the cell or the Internet. The emergence of these networks is driven by self-organizing processes that are governed by simple but generic laws. While unraveling the complex and interwoven systems
Wuchty, Stefan   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Bounded H∞ synchronization and state estimation for discrete time-varying stochastic complex for discrete time-varying stochastic complex networks over a finite horizon [PDF]

open access: yes, 2011
Copyright [2011] IEEE. This material is posted here with permission of the IEEE. Such permission of the IEEE does not in any way imply IEEE endorsement of any of Brunel University's products or services.
Liu, X   +5 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Kinetics of node splitting in evolving complex networks [PDF]

open access: yes, 2012
Copyright @ 2012 Elsevier B.V. All rights reserved. This is a preprint version of the published article which can be accessed at the link below.We introduce a collection of complex networks generated by a combination of preferential attachment and a ...
Colman, ER, Rodgers, GJ
core   +1 more source

Network community detection via neural embeddings

open access: yesNature Communications
Recent advances in machine learning research have produced powerful neural graph embedding methods, which learn useful, low-dimensional vector representations of network data. These neural methods for graph embedding excel in graph machine learning tasks
Sadamori Kojaku   +3 more
doaj   +1 more source

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