Results 101 to 110 of about 3,130,788 (278)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Network community detection via neural embeddings

open access: yesNature Communications
Recent advances in machine learning research have produced powerful neural graph embedding methods, which learn useful, low-dimensional vector representations of network data. These neural methods for graph embedding excel in graph machine learning tasks
Sadamori Kojaku   +3 more
doaj   +1 more source

Deep Complex Networks

open access: yes, 2018
At present, the vast majority of building blocks, techniques, and architectures for deep learning are based on real-valued operations and representations.
Bengio, Yoshua   +9 more
core  

Optimal routing on complex networks

open access: yes, 2006
We present a novel heuristic algorithm for routing optimization on complex networks. Previously proposed routing optimization algorithms aim at avoiding or reducing link overload. Our algorithm balances traffic on a network by minimizing the maximum node
B. Fortz   +5 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

150-Channel Four Wave Mixing Based Multiwavelength Brillouin-Erbium Doped Fiber Laser

open access: yesIEEE Photonics Journal, 2013
A wide band tunable multiwavelength Brillouin-erbium fiber laser (BEFL) is developed. In this structure, the laser is formed between a double pass amplification box and a highly nonlinear fiber (HNLF), which acts as a virtual mirror, results in removing ...
A. W. Al-Alimi   +5 more
doaj   +1 more source

Multi-fractal analysis of weighted networks [PDF]

open access: yes, 2014
In many real complex networks, the fractal and self-similarity properties have been found. The fractal dimension is a useful method to describe fractal property of complex networks.
Chen, Xiaowu   +5 more
core  

Attack vulnerability of complex networks

open access: yes, 2002
We study the response of complex networks subject to attacks on vertices and edges. Several existing complex network models as well as real-world networks of scientific collaborations and Internet traffic are numerically investigated, and the network ...
Han, Seung Kee   +3 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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