Results 51 to 60 of about 767,104 (296)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Exploring Organic-mineral Evolution in Planetary Analogs: Insights from Hydrothermal Alteration of Aromatic Molecules and Mafic Minerals

The Planetary Science Journal
Organic-mineral interactions are crucial drivers of diversity in abiotic systems on planetary surfaces. Despite their significance, the evolution of these systems, particularly the role of organic molecules in newly formed minerals, remains underexplored.
Vassilissa Vinogradoff, Vincent Chevrier, Olivier Grauby, Marie-Vanessa Coulet, Florence Chaspoul, John Carter   +5 more
doaj   +1 more source

The cometary composition of a protoplanetary disk as revealed by complex cyanides

, 2015
Observations of comets and asteroids show that the Solar Nebula that spawned our planetary system was rich in water and organic molecules. Bombardment brought these organics to the young Earth's surface, seeding its early chemistry.
A Dutrey, A Dutrey, C Brinch, C Favre, C Qi, C Qi, C Qi, C Walsh, C Walsh, C Walsh, C Walsh, Chunhua Qi, D Lynden-Bell, D Semenov, David J. Wilner, DM Graninger, DP O’Brien, E Bergin, E Dartois, E Herbst, EC Fayolle, EF van Dishoeck, EF van Dishoeck, EI Chiang, FJ Ciesla, GM Muñoz Caro, H Nomura, JS Carr, K Furuya, K Tsiganis, KA Rosenfeld, Karin I. Öberg, Kenji Furuya, KI Öberg, KI Öberg, KI Öberg, KJ Walsh, KM Pontoppidan, L Hartmann, LI Cleeves, LI Cleeves, M Dubernet, M Simon, M Takami, M Wernli, MJ Mumma, MP Collings, MR Hogerheijde, N Goldman, N Sakai, P D'Alessio, P Gratier, P Hartogh, RT Garrod, Ryan Loomis, S Guilloteau, S Pizzarello, Sean M. Andrews, T Yamamoto, V Piétu, V Wakelam, Viviana V. Guzmán, Y Aikawa, Y Aikawa, Yuri Aikawa   +64 more
core   +1 more source

Organic Electrosynthesis: Applications in Complex Molecule Synthesis

ChemElectroChem, 2019
AbstractOrganic electrosynthesis is an enabling and sustainable technology, which constitutes a rapidly expanding field of research. Electrochemical approaches serve as convenient and green alternatives to stoichiometric and toxic chemical redox agents.
Andrey Shatskiy, Helena Lundberg, Markus D. Kärkäs   +2 more
openaire   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Infrared Spectra of Organic and Salt-bearing Ices under Titan Conditions: Constraints on Detection of Ocean Materials

The Planetary Science Journal
Titan, with its organic-rich atmosphere and global subsurface ocean, has long been considered a prime candidate to potentially host life beyond Earth.
Paul V. Johnson, Robert Hodyss, Michael J. Malaska   +2 more
doaj   +1 more source

Chemical Evolution of Some Selected Complex Organic Molecules in Low-mass Star-forming Regions

The Astrophysical Journal, 2023
The destiny of complex organic molecules (COMs) in star-forming regions is interlinked with various evolutionary phases. Therefore, identifying these species in diversified environments of identical star-forming regions would help to understand their ...
Bratati Bhat, Rumela Kar, Suman Kumar Mondal, Rana Ghosh, Prasanta Gorai, Takashi Shimonishi, Kei E. I. Tanaka, Kenji Furuya, Ankan Das   +8 more
doaj   +1 more source

Static polarizability of molecular materials: environmental and vibrational contributions

, 2003
Modeling the dielectric behavior of molecular materials made up of large pi-conjugated molecules is an interesting and complex task. Here we address linear polarizabilities, and the related dielectric constant, of molecular crystals and aggregates made ...
Painelli, Anna, Soos, Zoltan G., Terenziani, Francesca   +2 more
core   +1 more source

Formation rates of complex organics in UV irradiated CH3OH-rich ices I: Experiments [PDF]

, 2009
(Abridged) Gas-phase complex organic molecules are commonly detected in the warm inner regions of protostellar envelopes. Recent models show that photochemistry in ices followed by desorption may explain the observed abundances.
Garrod, R. T., Linnartz, H., Oberg, K. I., van Dishoeck, E. F.   +3 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source