Results 61 to 70 of about 85,609 (247)
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Thermodynamic Analysis of the Phase Transition of Supper Austenitic Stainless Steel S31254
Teshugang, 2023 Super austenitic stainless steel （SASS） has been developed widely for industries like marine， environmental protection， chemical industry and other harsh conditions.
Zhang Wei +3 more
doaj
Latest Progress in Development of Cold-Rolled Complex Phase Steel
Metallurgical Engineering, 2016 先进高强度钢已经在汽车上得到了广泛应用，并在汽车的节能、安全、环保等方面表现出了广阔的前景。其与普通高强钢的区别在于它们的显微组织不同，普通高强钢是单相铁素体组织，而先进高强钢基本上是多相组织，主要强化方式为相变强化，其不仅具有高的强度，而且具有良好的成形性能、抗凹性能、能量吸收率高。本文简述了先进高强度复相钢的最新开发和研究进展情况，为复相钢的研究开发提供参考。 Advanced high strength steels (AHSS) are widely used in body-in-white to improve safety, energy saving and reduce emission.
openaire +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
MATEC Web of Conferences, 2013 The goal of this study is to understand the complex microstructures which form at the interface between a low-alloy steel and a stainless steel during welding and subsequent heat-treatment at 610 ∘C.
Mas Fanny +5 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source
Optimization of Induction Quenching Processes for HSS Roll Based on MMPT Model
Metals, 2019 To improve the comprehensive performance of high speed steel (HSS) cold rolls, the induction hardening processes were analyzed by numerical simulation and experimental research.
Ligang Liu +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source