Results 101 to 110 of about 267,312 (266)

Modified Wave-Front Propagation and Dynamics Coming from Higher-Order Double-Well Potentials in the Allen–Cahn Equations

Mathematics
In this paper, we conduct a numerical investigation into the influence of polynomial order on wave-front propagation in the Allen–Cahn (AC) equations with high-order polynomial potentials.
Junseok Kim
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Technique for the Determination of the Elastic Stiffness Coefficient of Interatomic Connection Based on the Experimental Weight-Loading Curve [PDF]

Журнал нано- та електронної фізики, 2012
Calculation technique of the elastic stiffness coefficient of interatomic binding and interatomic forces for the crystal lattice of the deformed body is presented.
K.D. Evfimko, A.A. Gaisha, A.A. Mochalov   +2 more
doaj  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Scalable training of neural network potentials for complex interfaces through data augmentation

npj Computational Materials
Artificial neural network (ANN) potentials enable accurate atomistic simulations of complex materials at unprecedented scales, but training them for potential energy surfaces (PES) of diverse chemical environments remains computationally intensive ...
In Won Yeu, Annika Stuke, Jon López-Zorrilla, James M. Stevenson, David R. Reichman, Richard A. Friesner, Alexander Urban, Nongnuch Artrith   +7 more
doaj   +1 more source

Assessment of Classical Force-Fields for Graphene Mechanics

Crystals
The unique properties of graphene have attracted the interest of researchers from various fields, and the discovery of graphene has sparked a revolution in materials science, specifically in the field of two-dimensional materials.
Zhiwei Ma, Yongkang Tan, Xintian Cai, Xue Chen, Tan Shi, Jianfeng Jin, Yifang Ouyang, Qing Peng   +7 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Harmonic potentials in the de Rham complex

CoRR
Representing vector fields by potentials can be a challenging task in domains with cavities or tunnels, due to the presence of harmonic fields which are both irrotational and solenoidal but may have no scalar or vector potentials. For harmonic fields normal to the boundary, which exist in domains with cavities, the standard approach is to construct ...
Martin Campos Pinto, Julian Owezarek
openaire   +2 more sources