Results 131 to 140 of about 8,737,420 (298)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Spectrum of twisted Dirac operators on the complex projective space $\Bbb P^{2q+1}(\Bbb C)$

open access: yes, 1989
summary:In this paper, we explicitly determine the spectrum of Dirac operators acting on smooth sections of twisted spinor bundles over the complex projective space $\Bbb P^{2q+1}(\Bbb C)$ for $q\geq 1$
Cahen, Michel   +3 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

CIRCLES AND HELICES IN A COMPLEX PROJECTIVE SPACE

open access: yes
This expository paper consists of two parts. One is to investigate lengths of closed helices in Euclidean sphere by using the information on lengths of closed circles in a complex projective space.
ADACHI, TOSHIAKI, Maeda, Sadahiro
core   +2 more sources

Spaces of algebraic maps from real projective spaces into complex projective spaces

open access: yes, 2008
We study the homotopy types of spaces of algebraic (rational) maps from real projective spaces into complex projective spaces. In a previous paper we have shown that the inclusion of the first space into the second one is a homotopy equivalence. In this paper we prove that the homotopy types of the terms of the natural "degree" filtration approximate ...
Kozlowski, Andrzej, Yamaguchi, Kohhei
openaire   +2 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Towards minimal self-testing of qubit states and measurements in prepare-and-measure scenarios

open access: yesNew Journal of Physics
Self-testing is a promising approach to certifying quantum states or measurements. Originally, it relied solely on the outcome statistics of the measurements involved in a device-independent (DI) setup.
Gábor Drótos   +3 more
doaj   +1 more source

SOME PROJECTIVE DISTANCE INEQUALITIES FOR SIMPLICES IN COMPLEX PROJECTIVE SPACE

open access: yes, 2014
. We prove inequalities relating the absolute value of the determi-nant of n + 1 linearly independent unit vectors in Cn+1 and the projective distances from the vertices to the hyperplanes containing the opposite faces of the simplices in complex ...
Mark Fincher   +2 more
core  

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