Results 81 to 90 of about 4,276,702 (282)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

The Local Structure of Space-Variant Images [PDF]

, 1996
Local image structure is widely used in theories of both machine and biological vision. The form of the differential operators describing this structure for space-invariant images has been well documented (e.g. Koenderink, 1984).
Cohen, Michael A., Fishl, Bruce, Schwartz, Eric L.   +2 more
core   +1 more source

Composite Operators in the Twistor Formulation of $\mathcal{N}=4$ SYM Theory

, 2016
We incorporate gauge-invariant local composite operators into the twistor-space formulation of $\mathcal{N}=4$ Super Yang-Mills theory. In this formulation, the interactions of the elementary fields are reorganized into infinitely many interaction ...
Koster, Laura, Mitev, Vladimir, Staudacher, Matthias, Wilhelm, Matthias   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Coherent States of $SU(l,1)$ groups

, 1993
This work can be considered as a continuation of our previous one (J.Phys., 26 (1993) 313), in which an explicit form of coherent states (CS) for all SU(N) groups was constructed by means of representations on polynomials. Here we extend that approach to
A L Shelepin, Bagrov V G, Bargmann V, Barut A O, Barut A O, Berezin F A, Berezin F A, Berezin F A, Berezin F A, Berezin F A, D M Gitman, Fronsdal C, Fronsdal C, Gelfand I M, Gitman D M, Gitman D M, Gitman D M, Joseph D W, Kinnersley M, Klauder I R, Klauder J R, Kobayashi S, Lieb E M, Malkin I A, Monastyrsky M I, Ottoson U, Perelomov A M, Perelomov A M, Shelepin A L, Shelepin L A, Smorodinski Ya A, Smorodinski Ya A, Tsu Yao, Vilenkin N Ya   +33 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Cross theorems with singularities

, 2009
We establish extension theorems for separately holomorphic mappings defined on sets of the form W\setminus M with values in a complex analytic space which possesses the Hartogs extension property.
B. Coupet, B. Josefson, B. Shiffman, E. Bedford, E. Bedford, E.A. Poletsky, E.A. Poletsky, E.M. Chirka, J.P. Rosay, M. Jarnicki, M. Jarnicki, M. Jarnicki, M. Jarnicki, M. Jarnicki, M. Jarnicki, M. Klimek, O. Alehyane, O. Alehyane, P. Pflug, P. Pflug, P. Pflug, P. Pflug, P. Pflug, Peter Pflug, S.M. Ivashkovich, V.-A. Nguyên, V.-A. Nguyên, V.-A. Nguyên, Viêt-Anh Nguyên   +28 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Spaces of complex functions and vector measures in incomplete spaces

Journal of Function Spaces and Applications, 2004
It is known that the space L1(μ) of complex functions which are integrable with respect to a vector measure μ taking values in a (not neessarily complete) locally convex space is not an ideal, in general. We discuss several natural properties which L1(μ)
Werner Riker, Martin Väth
doaj   +1 more source

A New Crystal Form of the SARS-CoV-2 Receptor Binding Domain: CR3022 Complex—An Ideal Target for In-Crystal Fragment Screening of the ACE2 Binding Site Surface

Frontiers in Pharmacology, 2020
In-crystal fragment screening is a powerful tool to chemically probe the surfaces used by proteins to interact, and identify the chemical space worth exploring to design protein-protein inhibitors.
Charlie Nichols, Charlie Nichols, Joseph Ng, Annika Keshu, Franca Fraternali, Gian F. De Nicola, Gian F. De Nicola   +6 more
doaj   +1 more source