Results 261 to 270 of about 13,893,592 (304)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

ATP-independent assembly machinery of bacterial outer membranes: BAM complex structure and function set the stage for next-generation therapeutics. [PDF]

Protein Sci
George A, Patil AG, Mahalakshmi R.
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

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The structural complexity of perovskites

Physical Chemistry Chemical Physics, 2022
Information theory is used to calculate structural complexities of various perovskite-type materials, showing that complexity scales with the size of the pseudocubic ReO 3 -type [BX 3 ] n −
Sebastian A. Hallweger, Clemens Kaußler, Gregor Kieslich   +2 more
openaire   +2 more sources

SCOTT COMPLEXITY OF COUNTABLE STRUCTURES

The Journal of Symbolic Logic, 2021
AbstractWe define the Scott complexity of a countable structure to be the least complexity of a Scott sentence for that structure. This is a finer notion of complexity than Scott rank: it distinguishes between whether the simplest Scott sentence is $\Sigma _{\alpha }$ , $\Pi _{\alpha }$ , or $\mathrm {d-}\Sigma _{\alpha }$ .
Rachael Alvir, Noam Greenberg, Matthew Harrison-Trainor, Dan Turetsky   +3 more
openaire   +2 more sources

REDUCTION OF STRUCTURAL COMPLEXITY

IFAC Proceedings Volumes, 1992
Abstract The identification of weakly coupled sub-systems often provides the basis for complex multi-variable control system design. Such identification is not always easy, and conventional methods of system reduction often make such an approach impossible.
Jan Jantzen, Frank Evans
openaire   +1 more source

On the Complex Structure of the Universe

Journal of Mathematical Physics, 1966
A complex space—time is constructed from physical axioms. Both gravitational and electromagnetic fields are approximations to parts of a geometric object defined on this complex space, while other parts may represent strong and weak interactions. The intersections of the singularities of the three independent geometric invariants are identified as ...
openaire   +2 more sources

Structuring complex requirements

ACM SIGSOFT Software Engineering Notes, 2007
Sets of requirements that analysts are dealing with are often big and complex. That makes requirements structuring one of the most important activities in requirements engineering, because of how requirements are structured and presented directly impacts the requirements development process and the quality of requirements.
openaire   +2 more sources

Fixed Structure Complexity

2008
We consider a non-standard parametrization, where, forproblems consisting of a combinatorial structure and a number, we parameterizeby the combinatorial structure, rather than by the number.For example, in the Short-Nondeterministic-Halt problem, which is todetermine if a nondeterministic machine M accepts the empty string int steps, we parameterize by
Yonatan Aumann, Yair Dombb
openaire   +2 more sources