Results 161 to 170 of about 2,361,537 (287)

Equation-free and variable free modeling for complex/multiscale systems. Coarse-grained computation in science and engineering using fine-grained models

, 2017
Ioannis G. Kevrekidis
openalex   +2 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Lessons from complex systems science for AI governance. [PDF]

Patterns (N Y)
Kolt N, Shur-Ofry M, Cohen R.
europepmc   +1 more source

Orthogonalization of complex cell-free production systems

, 2013
Sonja Billerbeck
openalex   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Fluorinated Phenylazopyrazoles for Monitoring the Photoisomerization in Complex Systems. [PDF]

Chemistry
Jakob L, van der Wal JJ, Tovtik R, Copko J, Iagatti A, Donato MD, Crespi S, Simeth NA.   +7 more
europepmc   +1 more source

Distributed architectures for diagnosis and prognosis of large scale complex technical systems

, 2010
Mickaël Diévart, CHARBONNAUD, Philippe
openalex   +1 more source

ON A MATURITY MODEL FOR COMPLEXITY, COMPLEX SYSTEMS, AND COMPLEX SYSTEMS ENGINEERING

International Journal of Design & Nature and Ecodynamics, 2016
openaire   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Understanding the mechanisms of climate change impact on tuberculosis: a complex systems approach. [PDF]

BMC Public Health
Shadi Y, Morasae EK, Khazaei S, Nasehi M, Sharafi S, Asakereh H, Tapak L, Kahramfar Z, Mohammadi Y.   +8 more
europepmc   +1 more source