Results 201 to 210 of about 2,361,537 (287)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Nature-Inspired Metaheuristic Optimization for Control Tuning of Complex Systems. [PDF]

Biomimetics (Basel)
Garicano-Mena J, Santos M.
europepmc   +1 more source

The policy of Merit-based Promotion in São Paulo state teaching system: a complex and multifaceted process

, 2015
Valéria de Araújo Ferreira Gregio de Souza
openalex   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Predicting the <i>Post</i>-Hartree-Fock Electron Correlation Energy of Complex Systems with the Information-Theoretic Approach. [PDF]

Molecules
Wang P, Hu D, Lu L, Zhao Y, Chen J, Ayers PW, Liu S, Zhao D.   +7 more
europepmc   +1 more source

CAE Analysis of Primary Shaft Systems in Great Five-Axis Turning-Milling Complex CNC Machine

, 2019
C.C. Hong, Cheng-Long Chang, Nai-Rui Ou, Chien-Yu Lin   +3 more
openalex   +1 more source

Bayesian nonparametric inference in mechanistic models of complex biological systems

, 2019
Umberto Noè
openalex   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Localizing Synergies of Hidden Factors in Complex Systems: Resting Brain Networks and HeLa GeneExpression Profile as Case Studies. [PDF]

Entropy (Basel)
Ontivero-Ortega M, Mijatovic G, Faes L, Rosas FE, Marinazzo D, Stramaglia S.   +5 more
europepmc   +1 more source

Results on solutions of several systems of the product type complex partial differential difference equations [PDF]

Xiao Lan Liu, Hong Yan Xu, Yi Hui Xu, Nan Li   +3 more
openalex   +1 more source