Results 61 to 70 of about 7,998,614 (283)

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

Terahertz waves dynamic diffusion in 3D printed structures

open access: yesScientific Reports, 2022
Applications of metamaterials in the realization of efficient devices in the terahertz band have recently been considered to achieve wave deflection, focusing, amplitude manipulation and dynamical modulation.
Mauro Missori   +2 more
doaj   +1 more source

Transparency in Complex Computational Systems [PDF]

open access: yes, 2019
Scientists depend on complex computational systems that are often ineliminably opaque, to the detriment of our ability to give scientific explanations and detect artifacts. Some philosophers have s..
Creel, Kathleen A.
core   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Data-Driven Quality Assurance: Defect Prediction to Reduce Carbon Footprint in Manufacturing Logistics [PDF]

open access: yesE3S Web of Conferences
In modern manufacturing environments, minimizing carbon emissions while maintaining product quality has become a strategic imperative. One critical yet often overlooked contributor to elevated CO₂ emissions is the occurrence of unexpected quality defects,
Douiri Rokaya   +3 more
doaj   +1 more source

Topic detection with recursive consensus clustering and semantic enrichment

open access: yesHumanities & Social Sciences Communications, 2023
Extracting meaningful information from short texts like tweets has proved to be a challenging task. Literature on topic detection focuses mostly on methods that try to guess the plausible words that describe topics whose number has been decided in ...
Vincenzo De Leo   +5 more
doaj   +1 more source

Studying complex adaptive systems using molecular classifier systems [PDF]

open access: yes, 2007
Complex Adaptive Systems (CAS) are dynamical networks of interacting agents occurring in a variety of natural and artificial systems (e.g. cells, societies, stock markets). These complex systems have the ability to adapt, evolve and learn from experience.
Decraene, James   +2 more
core  

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

Spliceator: multi-species splice site prediction using convolutional neural networks

open access: yesBMC Bioinformatics, 2021
Background Ab initio prediction of splice sites is an essential step in eukaryotic genome annotation. Recent predictors have exploited Deep Learning algorithms and reliable gene structures from model organisms.
Nicolas Scalzitti   +8 more
doaj   +1 more source

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