Results 81 to 90 of about 7,998,614 (283)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Leveraging gene correlations in single cell transcriptomic data
BMC BioinformaticsBackground Many approaches have been developed to overcome technical noise in single cell RNA-sequencing (scRNAseq). As researchers dig deeper into data—looking for rare cell types, subtleties of cell states, and details of gene regulatory networks—there
Kai Silkwood +5 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai +4 more
wiley +1 more source
Controlling protein activity by dynamic recruitment on a supramolecular polymer platform
Nature Communications, 2018 DNA-origami allows the precise recruitment of DNA-protein conjugates but lacks the dynamics found in natural protein assemblies. Here the authors present a synthetic polymer platform that combines the dynamics of supramolecular polymers with the ...
Sjors P. W. Wijnands +4 more
doaj +1 more source
Complex systems science: expert consultation report [PDF]
, 2009 Executive SummaryA new programme of research in Complex Systems Science must be initiated by FETThe science of complex systems (CS) is essential to establish rigorous scientific principles on which to develop the future ICT systems that are critical to ...
Bourgine, Paul +2 more
core
Perturbed Beta-Gamma Systems and Complex Geometry
, 2007 We consider the equations, arising as the conformal invariance conditions of the perturbed curved beta-gamma system. These equations have the physical meaning of Einstein equations with a B-field and a dilaton on a hermitian manifold, where the B-field 2-
Alekseev +36 more
core +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Complex network analysis of water distribution systems
, 2011 This paper explores a variety of strategies for understanding the formation, structure, efficiency and vulnerability of water distribution networks. Water supply systems are studied as spatially organized networks for which the practical applications of ...
Jeffrey, P., Yazdani, A.
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Out-of-equilibrium microcompartments for the bottom-up integration of metabolic functions
Nature Communications, 2018 Generating artificial cells able to carry out metabolic activities out-of-equilibrium is a current challenge in synthetic biology. Here the authors use a microfluidic platform for integration and analysis of minimal metabolic reactions in artificial ...
Thomas Beneyton +8 more
doaj +1 more source