Results 91 to 100 of about 7,998,614 (283)

Modeling Complex Systems [PDF]

Empirical observations suggest that linear dynamics are not an adequate representa- tion of ecological systems and that a realistic representation would require adoption of complex nonlinear dynamical systems with characteristics encountered in complex ...
XEPAPADEAS, Anastasios
core   +1 more source

From Simple to Complex and Ultra-complex Systems:\ud A Paradigm Shift Towards Non-Abelian Systems Dynamics [PDF]

, 2010
Atoms, molecules, organisms distinguish layers of reality because of the causal links that govern their behavior, both horizontally (atom-atom, molecule-molecule, organism-organism) and vertically (atom-molecule-organism).
Baianu, Prof.Dr. I.C,, Poli, Prof.Dr. Roberto   +1 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

HPV transmission and optimal control of cervical cancer in China

Scientific Reports
Cervical cancer (CC), the fourth most common female malignancy globally, is predominantly caused by persistent infection with high-risk human papillomavirus (HPV) strains.
Huarong Ren, Rui Xu, Juan Zhang
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Direct observation of a wakefield generated with structured light

Nature Communications
The use of structured light to control the phase velocity of the wake in laser-wakefield accelerators has generated significant interest for its ability to mitigate electron dephasing. Combining the diffraction-free properties of Bessel beams with spatio-
Aaron Liberman, Anton Golovanov, Slava Smartsev, Sheroy Tata, Igor A. Andriyash, Salome Benracassa, Eitan Y. Levine, Yang Wan, Eyal Kroupp, Victor Malka   +9 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Fabrication of 3D photonic band gap crystals for controlling the emission of light [PDF]

EPJ Web of Conferences
3D photonic band gap crystals can be used to manipulate light, for example to increase the emission of an emitter. An inverse woodpile photonic band gap crystal has been fabricated in silicon by FIB lithography and reactive ion etching.
Goodwin Melissa J., Vreman Timon J., Harteveld Cornelis A. M., Kamphuis Geert-Jan, Schulz Andreas S., Lagendijk Ad, Vos Willem L.   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source