Results 91 to 100 of about 15,720,626 (306)

Leveraging gene correlations in single cell transcriptomic data

BMC Bioinformatics
Background Many approaches have been developed to overcome technical noise in single cell RNA-sequencing (scRNAseq). As researchers dig deeper into data—looking for rare cell types, subtleties of cell states, and details of gene regulatory networks—there
Kai Silkwood, Emmanuel Dollinger, Joshua Gervin, Scott Atwood, Qing Nie, Arthur D. Lander   +5 more
doaj   +1 more source

The shocklet transform: a decomposition method for the identification of local, mechanism-driven dynamics in sociotechnical time series

EPJ Data Science, 2020
We introduce a qualitative, shape-based, timescale-independent time-domain transform used to extract local dynamics from sociotechnical time series—termed the Discrete Shocklet Transform (DST)—and an associated similarity search routine, the Shocklet ...
David Rushing Dewhurst, Thayer Alshaabi, Dilan Kiley, Michael V. Arnold, Joshua R. Minot, Christopher M. Danforth, Peter Sheridan Dodds   +6 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

On an irreducible theory of complex systems

, 2008
In the paper the description of complex systems in terms of self-organization processes of prime integer relations is presented. Remarkably, based on the integers and controlled by arithmetic only the description can picture complex systems by ...
Victor Korotkikh (9811187), Korotkikh, Galina Alexandra., Korotkikh, Victor., Galina Korotkikh (9811184)   +3 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Start-to-end modelling of laser-plasma acceleration, beam transport and dose deposition of very high-energy electrons for radiotherapy

Scientific Reports
The proposed radiotherapy using very high-energy electron (VHEE) beams generated by a laser-plasma accelerator has garnered significant interest due to its dose distribution capabilities and potential to address limitations of traditional photon-based ...
Rajakrishna Kalvala, Anton Golovanov, Arnaud Courvoisier, Tomer Friling, Eyal Kroupp, Lidan Grishko, Victor Malka   +6 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Static and dynamic properties of small-world connection topologies based on transit-stub networks [PDF]

, 2003
Many real complex networks are believed to belong to a class called small-world (SW) networks. SW networks are graphs with high local clustering and small distances between nodes. A standard approach to constructing SW networks consists of varying the
Huerta, Ramón, Aguirre Maeso, Carlos, Corbacho Abelaira, Fernando   +2 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Complex Systems + Systems Engineering = Complex Systems Engineeri

CoRR, 2006
10 pages.
openaire   +3 more sources