Results 111 to 120 of about 15,720,626 (306)

Designing and Understanding Forensic Bayesian Networks using Argumentation [PDF]

open access: yes, 2017
The rise of forensic evidence in court has confronted the legal domain with a number of difficulties. It appears that a communication gap may exist between forensic and legal experts.Judges, lawyers and other legal experts are accustomed to argumentative
Timmer, S.T.   +2 more
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Direct observation of a wakefield generated with structured light

open access: yesNature Communications
The use of structured light to control the phase velocity of the wake in laser-wakefield accelerators has generated significant interest for its ability to mitigate electron dephasing. Combining the diffraction-free properties of Bessel beams with spatio-
Aaron Liberman   +9 more
doaj   +1 more source

Function diagnostics of complex systems by fluctuations

open access: yes, 2010
The power-density function of noise spectrum of open and complex systems changes by the power of frequency. We show that the fluctuation origin and the noise-powered description are equivalent to describe the coloured noise powerdensity. This observation
Szász András   +2 more
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

The engineering of concurrent simulations of complex systems [PDF]

open access: yes, 2009
Concurrent process-oriented programming is a natural medium for simulating complex systems, particularly systems where many simple components interact in an environment (which may itself be complex).
Polack, Fiona A. C.   +6 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Fabrication of 3D photonic band gap crystals for controlling the emission of light [PDF]

open access: yesEPJ Web of Conferences
3D photonic band gap crystals can be used to manipulate light, for example to increase the emission of an emitter. An inverse woodpile photonic band gap crystal has been fabricated in silicon by FIB lithography and reactive ion etching.
Goodwin Melissa J.   +6 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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