Results 91 to 100 of about 2,811,643 (287)

Vector regression introduced

open access: yesJournal of Geodetic Science, 2014
This study formulates regression of vector data that will enable statistical analysis of various geodetic phenomena such as, polar motion, ocean currents, typhoon/hurricane tracking, crustal deformations, and precursory earthquake signals.
Mok Tik, Bâki Iz H.
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

100% of the zeros of the Riemann zeta-function are on the critical line

open access: yes, 2019
We consider a specific family of analytic functions $g_{\alpha,T}(s)$, satisfying certain functional equations and approximating to linear combinations of the Riemann zeta-function and its derivatives of the form $c_0\zeta(s)+c_1\frac{\zeta'(s)}{\log T}
Preobrazhenskaya, Tatyana   +1 more
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

COMPLEX METHOD OF SEEKING THE MAXIMUM OF NON-NEGATIVE FUNCTION OF TWO VARIABLES

open access: yesJixie qiangdu, 2018
The optimization problems of binary functions widely exist in many practical engineering problems,their global optimization methods have always been one of the hot research issues. A high effective method of global optimization to nonnegative binary functions was put forward basing on the maximum modulus theorem of the analytic function of complex ...
ZHANG Jing, SHI WenPu
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

On generation of Julia sets, Mandelbrot sets and biomorphs via a modification of the viscosity approximation method

open access: yesResults in Control and Optimization
Iterative methodology has been demonstrated to be an achievement in the age of fractals. A novel method based on the viscosity approximation approach, one of the most popular iterative techniques for identifying non-linear operator fixed points, for ...
Rimsha Babar, Wutiphol Sintunavarat
doaj   +1 more source

Combinatorial Optimization Method for Operation of Pumping Station with Adjustable Blade and Variable Speed Based on Experimental Optimization of Subsystem

open access: yesAdvances in Mechanical Engineering, 2014
A decomposition-dynamic programming aggregation method based on experimental optimization for subsystem was proposed to solve mathematical model of optimal operation for single pumping station with adjustable blade and variable speed.
Yi Gong, Jilin Cheng
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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