Results 141 to 150 of about 7,748,503 (383)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Complexity in Non-Pharmacological Caregiving Activities at the End of Life: An International Qualitative Study

open access: gold, 2012
Olav Lindqvist   +13 more
openalex   +2 more sources

Embracing complexity in biomaterials design

open access: gold, 2022
Helena S. Azevedo, Álvaro Mata
openalex   +1 more source

Performance-Effective and Low-Complexity Task Scheduling for Heterogeneous Computing

open access: yesIEEE Trans. Parallel Distributed Syst., 2002
H. Topcuoglu, S. Hariri, Minyou Wu
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

An mHealth Design to Promote Medication Safety in Children with Medical Complexity

open access: hybrid, 2023
Anna Jolliff   +10 more
openalex   +1 more source

Unraveling intratumoral complexity in metastatic dermatofibrosarcoma protuberans through single-cell RNA sequencing analysis [PDF]

open access: bronze, 2023
Lingling Ge   +7 more
openalex   +1 more source

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