Results 151 to 160 of about 1,562,922 (269)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Retracted: Processing Methods for Digital Image Data Based on the Geographic Information System

Complexity
null Complexity
doaj   +1 more source

Quantifying the failure modes of current one-step retrosynthesis models. [PDF]

Chem Sci
Tran SBA, Roh J, Coley CW.
europepmc   +1 more source

Carney Complex--Clarity and Complexity [PDF]

Journal of Clinical Endocrinology & Metabolism, 2000
openaire   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Retracted: Transformation of Nonmultiple Cluster Music Cyclic Shift Topology to Music Performance Style

Complexity
null Complexity
doaj   +1 more source

Impact of Education and Music Training on the Development of Abstract Thinking in the First Years of Schooling. [PDF]

Open Mind (Camb)
Morfoisse T, Becuwe S, Palu M, Watkins CP, Dehaene-Lambertz G, Dehaene S.   +5 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Retracted: Optimization of IoT-Based Motion Intelligence Monitoring System

Complexity
null Complexity
doaj   +1 more source

Hybrid Robust Beamforming Optimization for LEO Satellite Communications Under DOA Estimation Errors in Spectrum Sharing Scenarios. [PDF]

Sensors (Basel)
Wang Y, Xie X, Jia J.
europepmc   +1 more source