Results 171 to 180 of about 1,562,922 (269)

Retracted: Analysis of International Competitiveness of Multinational Corporations Based on Rough Sets

Complexity
null Complexity
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Retracted: Numerical Investigation on the Dynamic Characteristics of an Adjustable Power Turbine Used in Environmental Control System

Complexity
null Complexity
doaj   +1 more source

Correction to: Molecular Complexity Constrained Early Amino Acid Recruitment into the Genetic Code. [PDF]

Genome Biol Evol
europepmc   +1 more source

Association Between Right Ventricular Dysfunction and Coronary Angiographic Complexity in Patients With Acute Myocardial Infarction. [PDF]

Cureus
Faisal KM, Dey A, Tareq MNU, Hoque ME, Shahidullah M, Hoque MM, Hassan MM, Hossain S, Mannan MA, Akhter T.   +9 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Retracted: Prediction and Application of Computer Simulation in Time-Lagged Financial Risk Systems

Complexity
null Complexity
doaj   +1 more source

3D printed and virtual kidney models as learning tools to improve anatomical and spatial understanding of renal tumors: a pilot educational study (Rein-3D print students - UroCCR 219). [PDF]

3D Print Med
Margue G, Michiels C, Sarrazin J, Faessel M, Jambon E, Ricard S, Bladou F, Robert G, Sabatier J, Bos F, Bernhard JC.   +10 more
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Retracted: Photovoltaic Generation Prediction of CCIPCA Combined with LSTM

Complexity
null Complexity
doaj   +1 more source