Results 31 to 40 of about 6,001,676 (290)
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda +15 more
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Offdiagonal Complexity: A computationally quick complexity measure for graphs and networks [PDF]
A vast variety of biological, social, and economical networks shows topologies drastically differing from random graphs; yet the quantitative characterization remains unsatisfactory from a conceptual point of view.
Albert +12 more
core +2 more sources
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
On Descriptive Complexity, Language Complexity, and GB [PDF]
We introduce $L^2_{K,P}$, a monadic second-order language for reasoning about trees which characterizes the strongly Context-Free Languages in the sense that a set of finite trees is definable in $L^2_{K,P}$ iff it is (modulo a projection) a Local Set ...
Rogers, James
core +3 more sources
Simplicial Complexes are Game Complexes [PDF]
Strong placement games (SP-games) are a class of combinatorial games whose structure allows one to describe the game via simplicial complexes. A natural question is whether well-known parameters of combinatorial games, such as "game value", appear as invariants of the simplicial complexes. This paper is the first step in that direction.
Faridi, Sara +2 more
openaire +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Space Complexity vs. Query Complexity [PDF]
Combinatorial property testing deals with the following relaxation of decision problems: Given a fixed property and an input x, one wants to decide whether x satisfies the property or is “far” from satisfying it. The main focus of property testing is in identifying large families of properties that can be tested with a certain number of queries to the ...
Oded Lachish, Ilan Newman, Asaf Shapira
openaire +1 more source

