Results 51 to 60 of about 6,178,625 (296)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Systemic risk mitigation in supply chains through network rewiring

open access: yesScientific Reports
The networked nature of supply chains makes them susceptible to systemic risk, where local firm failures can propagate through interdependencies and lead to cascading supply chain disruptions.
Giacomo Zelbi   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Cliopatria - A geospatial database of world-wide political entities from 3400BCE to 2024CE

open access: yesScientific Data
The scientific understanding of the complex dynamics of global history – from the rise and spread of states to their declines and falls, from their peaceful interactions with economic or diplomatic exchanges to violent confrontations – requires, at its ...
James S. Bennett   +12 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Heat, health, and habitats: analyzing the intersecting risks of climate and demographic shifts in Austrian districts

open access: yesScientific Reports
The impact of hot weather on health outcomes of a population is mediated by a variety of factors, including its age profile and local green infrastructure.
Hannah Schuster   +3 more
doaj   +1 more source

Infinite Communication Complexity [PDF]

open access: yes, 2014
Suppose that Alice and Bob are given each an infinite string, and they want to decide whether their two strings are in a given relation. How much communication do they need? How can communication be even defined and measured for infinite strings? In this
Guillon, Pierre, Jeandel, Emmanuel
core   +3 more sources

On the complexity of linearizability [PDF]

open access: yesComputing, 2015
It was shown in Alur et al. [1] that the problem of verifying finite concurrent systems through Linearizability is in EXPSPACE. However, there was still a complexity gap between the easy to obtain PSPACE lower bound and the EXPSPACE upper bound. We show in this paper that Linearizability is EXPSPACE-complete.
openaire   +3 more sources

A Complex Lens for a Complex Eye [PDF]

open access: yesIntegrative and Comparative Biology, 2017
A key innovation for high resolution eyes is a sophisticated lens that precisely focuses light onto photoreceptors. The eyes of holometabolous larvae range from very simple eyes that merely detect light to eyes that are capable of high spatial resolution.
Aaron L, Stahl   +3 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

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