Results 31 to 40 of about 6,178,625 (296)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

On Descriptive Complexity, Language Complexity, and GB [PDF]

open access: yes, 1995
We introduce $L^2_{K,P}$, a monadic second-order language for reasoning about trees which characterizes the strongly Context-Free Languages in the sense that a set of finite trees is definable in $L^2_{K,P}$ iff it is (modulo a projection) a Local Set ...
Rogers, James
core   +3 more sources

Complex Complexes: Signaling at the TCR [PDF]

open access: yesImmunity, 1996
The focus of this review has been on the complexity of biochemical events at a very proximal position in the TCR signaling cascade. A number of proteins and protein–protein interactions have been described. It should be noted that the function of many of these proteins (e.g., Vav, Cbl, PI3K, and SLP-76) remains to be defined.
Wange, Ronald L, Samelson, Lawrence E
openaire   +2 more sources

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

Inequality in economic shock exposures across the global firm-level supply network

open access: yesNature Communications
For centuries, national economies have been engaging in international trade and production. The resulting international supply networks not only increase wealth for countries, but also allow for economic shocks to propagate across borders.
Abhijit Chakraborty   +4 more
doaj   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Average-Case Complexity

open access: yes, 2006
We survey the average-case complexity of problems in NP. We discuss various notions of good-on-average algorithms, and present completeness results due to Impagliazzo and Levin.
Bogdanov, Andrej, Trevisan, Luca
core   +4 more sources

Shape Complexity in Turbulence [PDF]

open access: yes, 1998
The shape complexity of irregular surfaces is quantified by a dimensionless area-volume measure. A joint distribution of shape complexity and size is found for level-set islands and lakes in two-dimensional slices of the scalar field of liquid-phase ...
Catrakis, Haris J., Dimotakis, Paul E.
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

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