Results 61 to 70 of about 6,178,625 (296)

The visibility complex

open access: yesProceedings of the ninth annual symposium on Computational geometry - SCG '93, 1993
We introduce the visibility complex (a 2-dimensional regular cell complex) of a collection of n pairwise disjoint convex obstacles in the plane. It can be considered as a subdivision of the set of free rays (i.e., rays whose origins lie in free space, the complement of the obstacles).
Michel Pocchiola, Gert Vegter
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The complexity of Solitaire

open access: yesTheoretical Computer Science, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Luc Longpré, Pierre McKenzie
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Binary Determinantal Complexity

open access: yes, 2015
We prove that for writing the 3 by 3 permanent polynomial as a determinant of a matrix consisting only of zeros, ones, and variables as entries, a 7 by 7 matrix is required.
Hüttenhain, Jesko, Ikenmeyer, Christian
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Sample Complexity Bounds on Differentially Private Learning via Communication Complexity [PDF]

open access: yes, 2015
In this work we analyze the sample complexity of classification by differentially private algorithms. Differential privacy is a strong and well-studied notion of privacy introduced by Dwork et al. (2006) that ensures that the output of an algorithm leaks
Feldman, Vitaly, Xiao, David
core   +1 more source

Quantum Hamiltonian Complexity

open access: yes, 2015
Constraint satisfaction problems are a central pillar of modern computational complexity theory. This survey provides an introduction to the rapidly growing field of Quantum Hamiltonian Complexity, which includes the study of quantum constraint ...
Gharibian, Sevag   +3 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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