Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Complexity analysis of a closed-loop supply chain for power battery recycling under government subsidies. [PDF]
Kadeer A, Wang X, He H, Dai L.
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Algorithmic complexity theory and the relative efficiency of financial markets
Financial economists usually assess market efficiency in absolute terms. This is to be viewed as a shortcoming. One way of dealing with the relative efficiency of markets is to resort to the efficiency interpretation provided by algorithmic complexity ...
Giglio, Ricardo +4 more
core
Morphological and structural complexity analysis of low-resource English-Turkish language pair using neural machine translation models. [PDF]
Acı M, Vuran Sarı N, İnan Acı Ç.
europepmc +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Utility of complexity analysis in electroencephalography and electromyography for automated classification of sleep-wake states in mice. [PDF]
Furutani N +7 more
europepmc +1 more source
Working Memory Decline in Alzheimer's Disease Is Detected by Complexity Analysis of Multimodal EEG-fNIRS. [PDF]
Perpetuini D +9 more
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Metacontrol Regulates Creative Thinking: An EEG Complexity Analysis Based on Multiscale Entropy. [PDF]
Qi H, Liu C.
europepmc +1 more source

