Results 161 to 170 of about 8,702,509 (349)

COMPLEXITY * SIMPLICITY * SIMPLEXITY [PDF]

open access: yes
“In the midst of order, there is chaos; but in the midst of chaos, there is order”, John Gribbin wrote in his book Deep Simplicity (p.76). In this dialectical spirit, we discuss the generative tension between complexity and simplicity in the theory and ...
Cunha, Miguel Pina e, Rego, Armenio
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Three-Layered Psychological Analysis of an Epidemic: Impact and Legacy of Covid-19

open access: yesInternational Journal of Psychoanalysis and Education, 2020
The global emergency caused by the spread of virus known as “Covid-19” caught many people by surprise, revealing the precariousness not only of health, but also of many other areas of our life, such as relationships, the economy, politics or the ...
Francesca Granier   +3 more
doaj  

Aesthetic complexity: practice and perception in art & design

open access: yes, 2010
My research investigates the aesthetics of visual complexity in the practice and perception of visual art and design. The aim is to understand visual complexity in terms of the relationship between the objective properties of images and subjective ...
Birkin, G
core  

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Implementing technological intelligence systems from the viewpoint of complexity theory

open access: yesIngeniería e Investigación, 2008
Technology currently plays a very important role in organisations’ development and competitiveness, thus requiring suitable handling. Technology management has been strengthened by integrating new systematically-applied concepts, such as technological ...
María Elena García Vergara   +2 more
doaj  

Resilient leadership amidst complexity [PDF]

open access: yes, 2014
Introduction: Amidst more than two decades of a discourse calling for third sector organisations to be more ‘businesslike’, there has been relatively little research about the strengths of being ‘nonprofit-like’. This paper draws on recent research which
Malcolm, Margy-Jean, Margy-Jean Malcolm
core  

Teaching complexity in public administration across the globe : an overview

open access: yes, 2018
As the contributions in this special issue show, there are ample examples of teaching programs at the nexus of complexity and public administration and its sub-fields.
Gerrits, Lasse, Ivanovic, Nevena
core   +1 more source

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