Results 161 to 170 of about 8,682,077 (303)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Challenges and opportunities of complexity theory in health care systems. [PDF]

J Taibah Univ Med Sci
A'aqoulah A, El-Metwally AA, Al Khateeb B, Alammari D, Alshahrani A, Aldubikhi A, Alsulami A, Fatani F, Innab N.   +8 more
europepmc   +1 more source

Correction: Complexity theory for the modern Chinese economy from an information entropy perspective: Modeling of economic efficiency and growth potential. [PDF]

PLoS One, 2020
Yan J, Feng L, Denisov A, Steblyanskaya A, Oosterom JP.   +4 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

The Role of Complexity Theory in Understanding Brain's Neuron-Glia Interactions. [PDF]

Eur J Neurosci
Di Chiano M, Milior P, Poulot-Becq-Giraudon Y, Lanfredini R, Milior G.   +4 more
europepmc   +1 more source

Complexity theory for the modern Chinese economy from an information entropy perspective: Modeling of economic efficiency and growth potential. [PDF]

PLoS One, 2020
Yan J, Feng L, Denisov A, Steblyanskaya A, Oosterom JP.   +4 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Behaviour settings, situated action and complexity theory. [PDF]

Philos Trans R Soc Lond B Biol Sci
Heft H.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Care professionals' accounts of providing support and treatment for people with co-occurring alcohol use disorder and depression in the North East of England, UK: A qualitative study informed by complexity theory. [PDF]

PLoS One
O'Donnell A, Kaner E, Hanratty B, Gilvarry E, Wigham S, Jackson K.   +5 more
europepmc   +1 more source