Results 51 to 60 of about 2,646,616 (265)

Complexity of equivalence relations and preorders from computability theory

, 2013
We study the relative complexity of equivalence relations and preorders from computability theory and complexity theory. Given binary relations $R, S$, a componentwise reducibility is defined by $ R\le S \iff \ex f \, \forall x, y \, [xRy \lra f(x) Sf(y)]
Ianovski, Egor, Miller, Russell, Ng, Keng Meng, Nies, Andre   +3 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Identifying and Ranking of Best Influential Spreaders With Extended Clustering Coefficient Local Global Centrality Method

IEEE Access
The detection and ranking of influential nodes in complex networks are crucial for various practical applications such as identifying potential drug targets in protein-to-protein interaction networks, critical devices in communication networks, key ...
Mondikathi Chiranjeevi, V Sateeshkrishna Dhuli, Murali Krishna Enduri, Linga Reddy Cenkeramaddi   +3 more
doaj   +1 more source

A review of the complexity approach to the study human (society)-nature interactions [PDF]

Glasnik Srpskog Geografskog Društva, 2010
Traditional approach to the study of society-nature interactions based on reductionism and linear causality is no longer fully capable of explaining complex dynamics of integrated socio-economic and natural systems. For this reason demands for complexity
Miljanović Dragana
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

A Novel Convex Combination-Based Mixed Centrality Measure for Identification of Influential Nodes in Complex Networks

IEEE Access
Exploring the significance of popular node’s impact in complex networks yields numerous advantages, such as improving network resilience and accelerating information dissemination.
Buran Basha Mohammad, V. Sateeshkrishna Dhuli, Murali Krishna Enduri, Linga Reddy Cenkeramaddi   +3 more
doaj   +1 more source

A critical Discussion of Complexity Theory: How does 'Complexity Thinking' improve our Understanding of Politics and Policymaking?

Complexity, Governance & Networks, 2017
In this article, we present a critical discussion of complexity theory. We ask: what does it really offer policy studies? We suggest that its stated advantages-- interdisciplinarity, theoretical novelty, and empirical advance--are generally exaggerated ...
Paul Cairney, Robert Geyer
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source