Results 71 to 80 of about 8,682,077 (303)

Convex Isolating Clustering Centrality to Discover the Influential Nodes in Large Scale Networks

open access: yesIEEE Access
Ranking influential nodes within complex networks offers invaluable insights into a wide array of phenomena ranging from disease management to information dissemination and optimal routing in real-time networking applications.
Buran Basha Mohammad   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

An Overview of the Theory of Computational Complexity [PDF]

open access: yesJournal of the ACM, 1971
The purpose of this paper is to outline the theory of computational complexity which has emerged as a comprehensive theory during the last decade. This theory is concerned with the quantitative aspects of computations and its central theme is the measuring of the difficulty of computing functions.
Juris Hartmanis, John E. Hopcroft
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Complexity theory for operators in analysis [PDF]

open access: yesProceedings of the forty-second ACM symposium on Theory of computing, 2010
We propose an extension of the framework for discussing the computational complexity of problems involving uncountably many objects, such as real numbers, sets and functions, that can be represented only through approximation. The key idea is to use a certain class of string functions as names representing these objects.
Akitoshi Kawamura, Stephen A. Cook
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Integrated System Responses for Families Impacted by Violence: A Scoping Review

open access: yesInternational Journal of Integrated Care
Introduction: Violence within families is a complex problem which significantly impacts health and wellbeing. Despite the ubiquitous call for integrated family violence service delivery, integrated approaches vary significantly and challenges to ...
Claire Gear   +4 more
doaj   +1 more source

The complexity of logical theories

open access: yesTheoretical Computer Science, 1980
AbstractIn this paper we introduce a method of encoding the computation of an alternating TM into a logical theory. The efficiency of the embedding we give together with the decision procedures, using Ehrenfencht games, which have been developed over the past few years, yield precise lower bounds for many decidable theories.
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy