Results 91 to 100 of about 8,682,077 (303)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
On the complexity of theories of permutations
Theoretical Computer Science, 1985 The first-order theory T of two permutations which commute is investigated and its decidability is proved. Moreover, we show that the computational complexity of the decision algorithm for SAT(T) - on NTM's and ATM's - is the same (for upper and lower bounds) as that of the theory of one permutation.
openaire +1 more source
Cryptology and Complexity Theories [PDF]
, 2007 Complexity Theories have recently been proposed as a basis for evaluation of crypto machine performance. They are compared to Shannon's model. They shed a new highlight on randomness notion. But it is stressed that the statistical point of view remains the more secure.
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
KARMAŞIKLIK PARADİGMASI IŞIĞINDA ÖRGÜT TEORİLERİNİN YENİDEN DEĞERLENDİRİLMESİ
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2016 1700’lü yıllardan günümüze kadar geçerli olan Newtoncu paradigma ile dünya tıpkı bir saat gibi işleyen bir makine gibi açıklanmaktadır. Bu paradigma ile dünya belirli kurallara göre işleyen doğrusal, öngörülebilir ve tanımlanabilir neden-sonuç ...
Gökben Bayramoğlu
doaj
IEEE Access, 2017 The chronic growth of networked complexities in today's world, now require highly efficient evolvable systems. However, diverse open issues and inabilities are facing urban planning practice and social sciences due to the limitations of artificial ...
Mohamed A. Hawas
doaj +1 more source
Complexity Theory for Splicing Systems
Theoretical Computer Science, 2007 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Remco Loos, Mitsunori Ogihara
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source