Results 81 to 90 of about 8,682,077 (303)

Some thoughts on social versus cultural complexity

open access: yesDocumenta Praehistorica, 2009
Socially complex hunter-gatherers are characterised by (1) inherited, permanent leadership and (2) sustained control over non-kin labour. Archaeologists have tended to infer social complexity through evidence of cultural complexity (i.e., artistic ...
Rastko Cvekić
doaj   +1 more source

Implications of Complexity Theory

open access: yes, 2021
Visions for Sustainability, No 16 (2021) - In ...
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Rethinking Educational Reforms Through a Complex Dynamical Systems Approach: Preliminary Report from an Empirical Research

open access: yesNortheast Journal of Complex Systems, 2019
Literature on educational reforms is rich of cases where changes have been attempted, without however to attain success. Likewise the Greek education system had experienced a lot of reforms, most of which have failed to make the intended changes and they
Eugenia Tsiouplis, Dimitrios Stamovlasis
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Making Sense of Assignment

open access: yesNordic Journal of Comparative and International Education, 2018
The primary aim of this paper is to narrow down the description of how school leaders interpret the assign-ment (the task) and identify the markers for how they look upon the conditions of doing a good job in Sweden. The aim is in the context of practice-
Sören Augustinsson   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Phase Change and the Limits of Resilience: A Physics-Inspired Lens on Societal Fragility and Collapse

open access: yesRecoletos Multidisciplinary Research Journal
Contemporary systemic disruptions in finance, supply chains, ecological regimes, governance and critical infrastructure often appear sudden, yet they usually reflect long periods of hidden stress, declining resilience, and structural weakening beneath ...
Russell John Walker
doaj   +1 more source

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