Results 71 to 80 of about 2,169,915 (306)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Compliance control as a part of Product Approval and Implementation Policy (case study of Insurance Company «ORANTA» Ltd.)

Путеводитель предпринимателя, 2020
Article describes the way of compliance control during the procedure of new insurance products creation and implementation in Insurance Company «ORANTA» Ltd., subsidiary of Holland group Achmea.
N. E. Savvina
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Dynamic Movement Primitives Modulation-Based Compliance Control for a New Sitting/Lying Lower Limb Rehabilitation Robot

IEEE Access
Compliant physical human-robot interaction (pHRI), as well as the accuracy and robustness of trajectory tracking, are crucial for rehabilitation robots. In this paper, a new sitting/lying lower limb rehabilitation robot, SUT-SLLRR, has been designed for ...
Jie Zhou, Yao Sun, Rong Song, Zhe Wei
doaj   +1 more source

Compliance Control of Slave Manipulator Using EMG Signal for Telemanipulation

Applied Sciences, 2020
Telemanipulation systems have been widely utilized in industrial, surgical, educational, and even military fields. One of the important issues is that when a robot interacts with environment or objects, it can damage the robot itself or the objects due ...
Bummo Ahn, Seong Young Ko, Gi-Hun Yang
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Compliance Control of a Cable-Driven Space Manipulator Based on Force–Position Hybrid Drive Mode

Aerospace
Multi-cable cooperative control is essential for cable-driven space manipulators to achieve in-orbit services such as fault spacecraft maintenance, fuel injection, on-orbit assembly, and orbital garbage removal.
Runhui Xiang, Hejie Xu, Xinliang Li, Xiaojun Zhu, Deshan Meng, Wenfu Xu   +5 more
doaj   +1 more source

Configuration-based compliance control of kinematically redundant robot arm Part I: Theoretical framework [PDF]

FME Transactions, 2017
When the robot endpoint compliance is dominantly influenced by the flexibility of its joints, the robot taskspace generalized stiffness matrix can be mapped onto jointspace using appropriate congruence transformation.
Petrović Petar B., Lukić Nikola A.
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Compliance control of conflict of interests in the general system of internal control and resource management

Social Development & Security, 2019
The results of the research published in the article will be useful to professionals directly or indirectly involved in the process of identification and resolution of conflicts of interest, to managers at all levels and to internal control and ...
Наталія Лойшина, Костянтин Кустріч, Микола Ткач, Сергій Левченко, Віталій Гетьманський   +4 more
doaj   +1 more source