Results 151 to 160 of about 26,202 (254)

Nonclinical Considerations for Support of Pregnancy and Lactation in Clinical Trials

Birth Defects Research, Volume 118, Issue 6, June 2026.
ABSTRACT Background Pregnant and breastfeeding individuals remain underrepresented in clinical drug development, leaving health care providers and patients with limited data to inform treatment decisions. Current practice relies heavily on nonclinical developmental and reproductive toxicity (DART) studies in animals, while clinical trials typically ...
Dinesh Stanislaus, Christopher J. Bowman, Kimberly C. Brannen, Sarah N. Campion, Laura M. Carlson, Stephan Chalon, Anthony M. DeLise, Claudia Demarta‐Gatsi, Brian P. Enright, Wendy Halpern, Shermaine Mitchell‐Ryan, Vicki Sutherland, Karen Thacker, Kary Thompson, Belen Tornesi, Steven Van Cruchten, Ronald L. Wange, Tacey White, Connie L. Chen   +18 more
wiley   +1 more source

Disseminated Intravascular Coagulation With a Predominant Thrombotic Phenotype in Severe Plasmodium falciparum Malaria: A Case Report. [PDF]

Cureus
Gisca E, Santos MG, Costa S, Santos CR, Araújo A.   +4 more
europepmc   +1 more source

A Study of Patients in Malaria and Complicated Malaria

Journal of Medical Science And clinical Research, 2018
openaire   +1 more source

Opportunities and Challenges for Surveillance of Congenital Anomalies in Sub‐Saharan Africa

Birth Defects Research, Volume 118, Issue 6, June 2026.
ABSTRACT Introduction Congenital anomalies (CA) are ranked as the 3rd and 4th leading cause of neonatal and under‐5 mortality, respectively. Over 30% of infants born with a serious CA are found in sub‐Saharan Africa. Yet there are few robust epidemiological data on the burden and distribution of CA and associated mortality, disability, and morbidity ...
Emma Kalk, Helen Louise Malherbe, Ushma C. Mehta, Daniel Mumpe‐Mwanja, Modiegi Dianah Diseko, Adejumoke Idowu Ayede, Phyllis Kisa, Caroline Bonareri Osoro, George Bello, Lee Fairlie, Audrey Chepkemoi, Hamisi K. Shabani, Ali Sie, Samrawit Abebaw Tegene, Robert Serunjogi, Aminkeng Zawuo Leke, Helen Dolk, Linda Barlow Mosha, on behalf of the sub‐Saharan African Congenital Anomalies Network (sSCAN)   +18 more
wiley   +1 more source

The impacts of biological invasions

Biological Reviews, Volume 101, Issue 3, Page 1255-1310, June 2026.
ABSTRACT The Anthropocene is characterised by a continuous human‐mediated reshuffling of the distributions of species globally. Both intentional and unintentional introductions have resulted in numerous species being translocated beyond their native ranges, often leading to their establishment and subsequent spread – a process referred to as biological
Phillip J. Haubrock, Teun Everts, Neil Angelo S. Abreo, Jamie Bojko, Victor Deklerck, James W. E. Dickey, Ana Clara S. Franco, Emili García‐Berthou, Stelios Katsanevakis, Natalia I. Kirichenko, Stefano Mammola, Martin A. Nuñez, Ben Parker, Riccardo Scalera, Ismael Soto, Diederik Strubbe, Ali Serhan Tarkan, Lorenzo Vilizzi, Tim Adriaens, Paride Balzani, Dagmara Błońska, Elizabeta Briski, Rein Brys, Amy L. Burgess, James E. Byers, Carlos Cano‐Barbacil, Giuseppe Castaldelli, Jaimie T.A. Dick, Victoria Dominguez Almela, Romina D. Dimarco, Margarita Florencio, Antonín Kouba, Melina Kourantidou, Irmak Kurtul, Irene Martín‐Forés, Olivier Morissette, Julian D. Olden, Bruno E. Soares, Jakub Truszkowski, Hugo Verreycken, Marc Kenis, Ronaldo Sousa, J. Robert Britton   +42 more
wiley   +1 more source

Differential expression of mitochondria-associated genes in clinical samples of Plasmodium falciparum showing severe manifestations. [PDF]

BMC Genomics
Gujarati S, Singal BR, Gupta D, Kochar SK, Kochar DK, Das A.   +5 more
europepmc   +1 more source

New Insights Into the Role of Neutrophils in Lymphoma

Cancer Medicine, Volume 15, Issue 6, June 2026.
Tissue‐resident neutrophils challenge conventional paradigms by actively infiltrating normal lymphoid organs, predominantly localizing in interstitial compartments, a spatial distribution distinct from their classical vascular positioning. Neutrophils in lymphoid organs exhibit unique phenotypic and functional signatures, suggesting they play roles in ...
Ling Gu
wiley   +1 more source

Clinical and biological features of complicated and asymptomatic malaria among PLHIV and HIV-negative adults: An observational study in Libreville, Gabon. [PDF]

PLoS One
Moutombi Ditombi BC, Manomba Boulingui C, Mbang Nguema OA, Mihindou CJ, Pongui Ngondza B, Ndong Ngomo JM, Essomeyo Mebale M, Ntsame Owono MM, Mabicka Moussavou AD, Mayandza C, Mbondoukwé NP, Kono HN, Bouyou Akotet MK.   +12 more
europepmc   +1 more source

Anti‐Inflammatory Potential of Key Phytochemicals From Humboldtia sanjappae: In Vivo Studies and Molecular Docking With MM‐GBSA Analysis

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Humboldtia sanjappae bark extract evaluated for its anti‐inflammatory potential using in vivo paw edema models and in silico molecular docking. Bioactive flavonoids, particularly neoeriocitrin, showed strong interactions with TNF‐α, COX‐2, IL‐6, and IL‐1β, highlighting the extract's multi‐target anti‐inflammatory activity and therapeutic promise ...
Jameema Sidhic, Madhu Tanya Singh, Sruthi Mohan C. K., Aparna Prasad, Paromita Sarbadhikary, Praveen Thaggikuppe Krishnamurthy, Sulaiman C. T., Arunaksharan Narayanankutty, Heidi Abrahamse, Satheesh George, Blassan P. George   +10 more
wiley   +1 more source

Francesco Torti (1658-1741) and his description on the therapeutic use of quinine: the first effective method of treating malaria based on an extract of the bark of the Peruvian cinchona tree. [PDF]

Malariaworld J
Artico M, Costi R, Gazzaniga V, Iorio S, Pastore FS, Cofone L.   +5 more
europepmc   +1 more source