Results 121 to 130 of about 1,637,221 (372)

Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022
Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh, Rachel S. Kasper, Jessie Sanford, Chia‐Ling Phuah, Jason Hassenstab, Carlos Cruchaga   +5 more
wiley   +1 more source

BCG OSTEITIS

Acta Medica Iranica, 2004
The only available vaccine against tuberculosis is BCG which has been found to protect children against disseminated tuberculosis and tuberculous meningitis. BCG is one of the safest vaccines being used, and osteitis is a rare complication of it.
Kh. Daneshjou, M. Farzan, M.R. Giti A. Zamani   +2 more
doaj  

Establishment and biological characterization of radioresistant colorectal cancer cell lines

FEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu, Qing Dai, Jing Leng, Lin Fang, Jing‐Jing Ma, Rui Chen, Che Chen, Peng‐Fei Ran, Wen‐Wen Zhou, Chang Liu, Huang‐Fei Yu   +10 more
wiley   +1 more source

The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee, Graeme S. V. McDowell, Darryl C. De Vivo, Daniel Friedman, Samuel F. Berkovic, Maria Spanou, Argirios Dinopoulos, Katheryn Grand, Pedro A. Sanchez‐Lara, Michelle Allen‐Sharpley, Jodi Warman‐Chardon, Alexander Solyom, Thierry Levade, Edward H. Schuchman, Steffany A. L. Bennett, David A. Dyment, Toni S. Pearson   +16 more
wiley   +1 more source

Identifying effects of the use of fundal pressure in causing complication from the time of the woman\'s entrance into the delivery room to the time of discharging from the hospital (1994).

نشریه پرستاری ایران, 1996
This is a semi experimental survey with the main goal of identifying effects of the use of fundal pressure in causing complication from the time of the woman,s entrance into the delivery room to the time of discharge from the hospital.
Farydeh Parsaie, , ,
doaj  

Stabilizations of Heegaard splittings of sufficiently complicated 3-manifolds (Preliminary Report) [PDF]

arXiv, 2008
We construct families of manifolds that have pairs of genus $g$ Heegaard splittings that must be stabilized roughly $g$ times to become equivalent. We also show that when two unstabilized, boundary-unstabilized Heegaard splittings are amalgamated by a "sufficiently complicated" map, the resulting splitting is unstabilized.
arxiv  

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

COVID‐19 and the risk of Alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosis

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1953-1961, December 2022., 2022
Abstract Background The coronavirus disease 2019 (COVID‐19) pandemic has had an unprecedented impact on the healthcare system, economy, and society. Studies have reported that COVID‐19 may cause various neurologic symptoms, including cognitive impairment.
Hanyu Zhang, Zengyuan Zhou
wiley   +1 more source

Heegaard structure respects complicated JSJ decompositions [PDF]

arXiv, 2009
Let $M$ be a 3-manifold with torus boundary components $T_1$ and $T_2$. Let $\phi \colon T_1 \to T_2$ be a homeomorphism, $M_\phi$ the manifold obtained from $M$ by gluing $T_1$ to $T_2$ via the map $\phi$, and $T$ the image of $T_1$ in $M_\phi$. We show that if $\phi$ is "sufficiently complicated" then any incompressible or strongly irreducible ...
arxiv  

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source