Results 71 to 80 of about 1,863,875 (293)

Analysis, Simulation and Control of a New Measles Epidemic Model [PDF]

, 2019
In this paper the problem of modeling and controlling the measles epidemic spread is faced. A new model is proposed and analysed; besides the categories usually considered in measles modeling, the susceptible, the exposed, the infected, the removed and,
DI GIAMBERARDINO, Paolo, Iacoviello, Daniela   +1 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Determinants of outcomes in chronic pediatric peritoneal dialysis: a single center experience

The Turkish Journal of Pediatrics, 2020
Background. In situations where it may take a long time to perform renal transplantation peritoneal dialysis may become a long-term maintenance treatment, especially in countries with low donor rates.
Tariq Asi, Serdar Tekgül, Fazıl T Aki, Fatih Özaltın, Bora Gülhan, Ali C Bozacı, Ömer F Bahadır, Gökhan Karakurt, Hasan S Doğan, Ali Düzova, Rezzan Topaloğlu   +10 more
doaj   +1 more source

Quality Improvement on the Long-term Care Ventilator Unit: Interventions to Increase Patient Safety and Prevent Patient Harm [PDF]

, 2019
BACKGROUND: Tracheostomy patients are susceptible to life-threatening emergencies when their airways are compromised. Epidemiologic data suggests that 3.2% to 30% of tracheostomy patents have a complication. The long-term care ventilator unit (LTCVU) is
Anderson, Billie, Samuels, Joanne
core   +1 more source

The eVALuate study: two parallel randomised trials, one comparing laparoscopic with abdominal hysterectomy, the other comparing laparoscopic with vaginal hysterectomy [PDF]

, 2004
OBJECTIVE: To compare the effects of laparoscopic hysterectomy and abdominal hysterectomy in the abdominal trial, and laparoscopic hysterectomy and vaginal hysterectomy in the vaginal trial.
Abbott, J., Bridgman, S., Brown, J., Clayton, R., Fountain, J., Garry, R., Hawe, J., Lilford, R., Mason, S., Napp, V., Phillips, G., Whittaker, M.   +11 more
core   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Punch biopsies in tattooed skin: Complications and patient‐reported outcomes

JEADV Clinical Practice
Background Despite the popularity and usage of tattoos in modern society, various complications can occur such as allergic tattoo reactions, infections, tattoo removal complications and chronic granulomatous inflammatory tattoo reactions such as ...
Mila Poelhekken, Ines J. Schornagel, Sebastiaan A. S. van derBent   +2 more
doaj   +1 more source

Preoperative Narcotic Use, Impaired Ambulation Status, and Increased Intraoperative Blood Loss Are Independent Risk Factors for Complications Following Posterior Cervical Laminectomy and Fusion Surgery. [PDF]

, 2019
ObjectiveThis retrospective cohort study seeks to identify risk factors associated with complications following posterior cervical laminectomy and fusion (PCLF) surgery.MethodsAdults undergoing PCLF from 2012 through 2018 at a single center were ...
Badiee, Ryan K, Chan, Andrew K, Chou, Dean, Doherty, Brianna R, Molinaro, Annette, Mummaneni, Praveen V, Riew, K Daniel, Rivera, Joshua, Tan, Lee A   +8 more
core  

Extrahepatic complications of liver transplantation. [PDF]

, 1985
The massive surgical assault associated with hepatic transplantation makes a high frequency of complications almost inevitable. In this review of 225 patient records, selected at random from cases of liver transplantation in Pittsburgh over a 2 1/2 year ...
Shaw, BW, Starzl, TE, Wood, RP
core   +1 more source