Results 1 to 10 of about 5,841,357 (416)

Cardiovascular Autonomic Neuropathy in Type 1 Diabetes Is Associated With Disturbances in TCA, Lipid, and Glucose Metabolism

Frontiers in Endocrinology, 2022
IntroductionDiabetic cardiovascular autonomic neuropathy (CAN) is associated with increased mortality and morbidity. To explore metabolic mechanisms associated with CAN we investigated associations between serum metabolites and CAN in persons with type 1
Christian S. Hansen, Tommi Suvitaival, Simone Theilade, Simone Theilade, Simone Theilade, Ismo Mattila, Maria Lajer, Kajetan Trošt, Linda Ahonen, Tine W. Hansen, Cristina Legido-Quigley, Peter Rossing, Peter Rossing, Tarunveer S. Ahluwalia, Tarunveer S. Ahluwalia   +14 more
doaj   +1 more source

Renal Tumors in Pregnancy: A Case Report Focusing on the Timing of the Surgery and Patient Positioning

Case Reports in Obstetrics and Gynecology, 2022
Management of renal mass during pregnancy is challenging. There is no consensus regarding the fundamental timing issues (which trimester) of the interventions and patient positioning during the procedures.
Hamidreza Ghorbani, Mahdi Mottaghi, Salman Soltani   +2 more
doaj   +1 more source

Novel topical allogeneic bone-marrow-derived mesenchymal stem cell treatment of hard-to-heal diabetic foot ulcers: a proof of concept study

Stem Cell Research & Therapy, 2022
Aim The aim of this study was to investigate safety of treating diabetic foot ulcers with a topically administered mesenchymal stem cell product. Method Individuals with diabetes, peripheral neuropathy, toe blood pressure > 39 mmHg and non-infected foot ...
Jonas Askø Andersen, Anne Rasmussen, Marie Frimodt-Møller, Susanne Engberg, Esther Steeneveld, Klaus Kirketerp-Møller, Timothy O’Brien, Peter Rossing   +7 more
doaj   +1 more source

Cardiovascular characterisation of a novel mouse model that combines hypertension and diabetes co-morbidities

Scientific Reports, 2023
Epidemiologic data suggest that the prevalence of hypertension in patients with diabetes mellitus is ∼1.5–2.0 times greater than in matched non-diabetic patients.
Arpeeta Sharma, Judy S. Y. Choi, Anna M. D. Watson, Leila Li, Thomas Sonntag, Man K. S. Lee, Andrew J. Murphy, Miles De Blasio, Geoffrey A. Head, Rebecca H. Ritchie, Judy B. de Haan   +10 more
doaj   +1 more source

Translation, Linguistic Validation, and Cultural Adaptation of the Bladder Cancer Index (BCI) Questionnaire Into the Persian (Farsi) Language and Comparing it With WHO Quality of Life Questionnaire: An Observational Study

Journal of Family and Reproductive Health, 2023
Objective: Whether ileal conduit diversion (ICD) or orthotopic neobladder (ONB) urinary diversion provides better quality of life (QoL) is still under debate. The Bladder Cancer Index (BCI) is a specific tool for bladder cancer (BCa) patients, providing
Hamidreza Ghorbani, Monavar AfzalAghai, Salman Soltani, Mahdi Mottaghi, Mahmoud Tavakkoli, Amin Lotfi   +5 more
doaj   +1 more source

Impact of time‐restricted feeding on kidney injury in male rats with experimental metabolic syndrome

Experimental Physiology, 2023
Disruptions to circadian rhythm may be implicated in the pathogenesis of metabolic syndrome (Met‐S). For example, eating during an extended period of the day may negatively impact the circadian rhythms governing metabolic control, contributing, therefore,
Rajendran Harishkumar, Eva M. Baranda‐Alonso, William P. Martin, Neil G. Docherty   +3 more
doaj   +1 more source

miR-379 deletion ameliorates features of diabetic kidney disease by enhancing adaptive mitophagy via FIS1

Communications Biology, 2021
Kato, Abdollahi et al. identify a redox protein thioredoxin and mitochondrial fission-1 (FIS1) protein as miR-379 targets in mouse kidney. They find that miR-379 knockout mice are protected from diabetic kidney disease by enhancing mitophagy via FIS1 ...
Mitsuo Kato, Maryam Abdollahi, Ragadeepthi Tunduguru, Walter Tsark, Zhuo Chen, Xiwei Wu, Jinhui Wang, Zhen Bouman Chen, Feng-Mao Lin, Linda Lanting, Mei Wang, Janice Huss, Patrick T Fueger, David Chan, Rama Natarajan   +14 more
doaj   +1 more source

A cohort study of membranous nephropathy, primary or secondary

BMC Nephrology, 2021
Background Although IgG4 deposit against phospholipase A2 receptor (anti-PLA2R) is predominantly presented in the renal biopsy of patients with primary membranous nephropathy (MN), its diagnostic value of this immune complex has not been fully ...
Maryam Arghiani, Boshra Hasan Zamani, Fatemeh Nazemian, Sara Samadi, Malihe Saber Afsharian, Mahmoud Habibzadeh, Saeid Eslami, Mahin Ghorban Sabbagh   +7 more
doaj   +1 more source

Angiotensin II-Induced Long Non-Coding RNA Alivec Regulates Chondrogenesis in Vascular Smooth Muscle Cells

Cells, 2021
Long non-coding RNAs (lncRNAs) play key roles in Angiotensin II (AngII) signaling but their role in chondrogenic transformation of vascular smooth muscle cells (VSMCs) is unknown.
Vishnu Amaram Samara, Sadhan Das, Marpadga A. Reddy, Vinay Singh Tanwar, Kenneth Stapleton, Amy Leung, Maryam Abdollahi, Rituparna Ganguly, Linda Lanting, Rama Natarajan   +9 more
doaj   +1 more source

Fibroblast Growth Factor 21 Attenuates Diabetes-Induced Renal Fibrosis by Negatively Regulating TGF-β-p53-Smad2/3-Mediated Epithelial-to-Mesenchymal Transition via Activation of AKT [PDF]

Diabetes & Metabolism Journal, 2020
BackgroundEpithelial-to-mesenchymal transition (EMT) is required for renal fibrosis, which is a characteristic of diabetic nephropathy (DN). Our previous study demonstrated that fibroblast growth factor 21 (FGF21) prevented DN associated with the ...
Sundong Lin, Lechu Yu, Yongqing Ni, Lulu He, Xiaolu Weng, Xuemian Lu, Chi Zhang   +6 more
doaj   +1 more source