Results 61 to 70 of about 6,001,301 (391)

Oncology and complications

Archivio Italiano di Urologia e Andrologia, 2021
This collection of cases describes some unusual urological tumors and complications related to urological tumors and their treatment. Case 1: A case of uretero-arterial fistula in a patient with long-term ureteral stenting for ureteral oncological stricture and a second case associated to retroperitoneal fibrosis were described.
Diego Meo, Charalampos Mamoulakis, Massimo Lazzeri, Helen A. Papadaki, Evangelia Kyriazi, Vincenzo Magnano San Lio, Georgios Stathouros, Ioannis Glykas, Francesco Persico, Charalampos Pontikoglou, Giuseppe Giordano, Rodolfo Hurle, Charalampos Fragkoulis, Charalampos Mavridis, Irene Giagourta, Giovanni Lughezzani, Piergiorgio Gatto, George Georgiadis, George Piaditis   +18 more
openaire   +5 more sources

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

FEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa, Cong Lin, Irina A. Talyzina, Marina V. Goncharuk, Eduard V. Bocharov, Alexander S. Arseniev, Xiaohui Wang, Sergey A. Goncharuk, Konstantin S. Mineev   +8 more
wiley   +1 more source

Recent advances in the treatment of patients with obesity and chronic kidney disease

Annals of Medicine, 2023
Obesity is a chronic disease characterised by excess adiposity, which impairs health. The high prevalence of obesity raises the risk of long-term medical complications including type 2 diabetes and chronic kidney disease.
Roshaida Abdul Wahab, Ricardo V. Cohen, Carel W. le Roux   +2 more
doaj   +1 more source

Effects of the increase in co-payments from 20 to 30 percent on the compliance rate of patients with hypertension or diabetes mellitus in the Employed Health Insurance System [PDF]

, 2005
Objectives: How to contain medical expenditures is a universal problem. The Japanese government has increased patient co-payments to control it. The purpose of this study is to clarify whether the increase in co-payments to 30 percent prevented patients ...
Babazono, Akira, Imatoh, Takuya, Miyazaki, Motonobu, Tanaka, Kiyoshi, Tanihara, Shinichi, Tsuda, Toshihide, Une, Hiroshi, Yamamoto, Eiji   +7 more
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Murine Nephrotoxic Nephritis as a Model of Chronic Kidney Disease

International Journal of Nephrology, 2018
Using the nonaccelerated murine nephrotoxic nephritis (NTN) as a model of chronic kidney disease (CKD) could provide an easily inducible model that enables a rapid test of treatments.
M. K. E. Ougaard, P. H. Kvist, H. E. Jensen, C. Hess, I. Rune, H. Søndergaard   +5 more
doaj   +1 more source

Cellular death, reactive oxygen species (ROS) and diabetic complications

Cell Death and Disease, 2018
Chronic or intermittent hyperglycemia is associated with the development of diabetic complications. Several signaling pathways can be altered by having hyperglycemia in different tissues, producing oxidative stress, the formation of advanced glycation ...
C. Volpe, Pedro Henrique Villar-Delfino, Paula Martins Ferreira dos Anjos, J. A. Nogueira-Machado   +3 more
semanticscholar   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Predictive factors of neurological complications and one-month mortality after liver transplantation. [PDF]

, 2014
BackgroundNeurological complications are common after orthotopic liver transplantation (OLT). We aimed to characterize the risk factors associated with neurological complications and mortality among patients who underwent OLT in the post-model for end ...
Akhtar, Shahrzad, DiNorcia, Joseph, Fu, Katherine A, Kalayjian, Laura A, Sanossian, Nerses, Sher, Linda, Velani, Shamsha A   +6 more
core   +1 more source