Results 101 to 110 of about 4,843,847 (318)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Evaluation of IDB Action Plan for Private Sector Development in C&D Countries [PDF]

open access: yes, 2006
This paper (RE-319) presents the evaluation of the Action Plan in support of private sector development in C&D Countries performed by the Office of Evaluation and Oversight.
Inter-American Development Bank
core   +1 more source

Process-Based Information Systems Development: Taking Advantage of a Component-Based Infrastructure

open access: yesBusiness Systems Research, 2017
Background: Owing to the highly competitive business environment in which contemporary organizations have to operate, a quick and effective way of developing and maintaining information systems is of utmost importance to their success.
Pereira José Luís   +1 more
doaj   +1 more source

Component-Based Software Development [PDF]

open access: yes, 2004
Component-based software development (CBD) is an emerging discipline that promises to take software engineering into a new era. Building on the achievements of object-oriented software construction, CBD aims to deliver software engineering from a cottage industry into an industrial age for Information Technology, wherein software can be assembled from ...
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Research Article Software Component Selection Based on Quality Criteria Using the Analytic Network Process

open access: yes, 2014
Component based software development (CBSD) endeavors to deliver cost-effective and quality software systems through the selection and integration of commercially available software components.
Nazir, Shah   +8 more
core  

Microenterprise Development Review: Volume 5 : No. 1 : August, 2002

open access: yes, 2002
The first article of this edition of the Microenterprise Development Review examines the relationship between microfinance institutions and private international investors.
Inter-American Development Bank
core   +1 more source

Technical Note: Policy-Based Lending at the IDB

open access: yes, 2023
This note presents findings and insights from different sources and constitutes the first building block for the Office of Evaluation and Oversights (OVE) policy-based lending evaluation.
Inter-American Development Bank
core   +1 more source

A Component-based Software Development and Execution Framework for CAx Applications

open access: yesActa Polytechnica, 2004
Digitalization of the manufacturing process and technologies is regarded as the key to increased competitive ability. The MZ-Platform infrastructure is a component-based software development framework, designed for supporting enterprises to enhance ...
N. Matsuki, H. Tokunaga, H. Sawada
doaj  

SENP1‐Mediated HSP90ab1 DeSUMOylation in Cardiomyocytes Prevents Myocardial Fibrosis by Paracrine Signaling

open access: yesAdvanced Science
Myocardial infarction (MI) triggers a poor ventricular remodeling response, but the underlying mechanisms remain unclear. Here, the authors show that sentrin‐specific protease 1 (SENP1) is downregulated in post‐MI mice and in patients with severe heart ...
Zhihao Liu   +20 more
doaj   +1 more source

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