Results 61 to 70 of about 608,403 (284)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
2-Vertex Connectivity in Directed Graphs
, 2015 We complement our study of 2-connectivity in directed graphs, by considering the computation of the following 2-vertex-connectivity relations: We say that two vertices v and w are 2-vertex-connected if there are two internally vertex-disjoint paths from ...
AL Buchsbaum +6 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Examining resting-state functional connectivity in first-episode schizophrenia with 7T fMRI and MEG
NeuroImage: Clinical, 2019 Schizophrenia is often characterized by dysconnections in the brain, which can be estimated via functional connectivity analyses. Commonly measured using resting-state functional magnetic resonance imaging (fMRI) in order to characterize the intrinsic or
Kristin K. Lottman +5 more
doaj +1 more source
Resting-state functional connectivity is modulated by cognitive reserve in early Parkinson’s disease
Frontiers in Psychology, 2023 BackgroundFronto-striatal disconnection is thought to be at the basis of dysexecutive symptoms in patients with Parkinson’s disease (PD). Multiple reserve-related processes may offer resilience against functional decline.
Sonia Di Tella +6 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Remote Sensing, 2015 Search-centric, sample supervised image segmentation has been demonstrated as a viable general approach applicable within the context of remote sensing image analysis.
Christoff Fourie
doaj +1 more source
Strongly connected components-Algorithm for finding the strongly connected components of a graph
CoRR, 2018 A directed graph G (V, E) is strongly connected if and only if, for a pair of vertices X and Y from V, there exists a path from X to Y and a path from Y to X. In Computer Science, the partition of a graph in strongly connected components is represented by the partition of all vertices from the graph, so that for any two vertices, X and Y, from the same
openaire +2 more sources
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Minimal vertex covers on finite-connectivity random graphs - a hard-sphere lattice-gas picture
, 2000 The minimal vertex-cover (or maximal independent-set) problem is studied on random graphs of finite connectivity. Analytical results are obtained by a mapping to a lattice gas of hard spheres of (chemical) radius one, and they are found to be in ...
A. Barrat +44 more
core +2 more sources