Results 201 to 210 of about 7,641,023 (289)

Distinct Bone Marrow Metabolic Profiles at Relapse Compared with Initial Diagnosis in Pediatric Acute Lymphoblastic Leukemia-An LC-MS Metabolomics Study. [PDF]

Cancers (Basel)
Dissook S, Kittichaiworakul R, Thongkumkoon P, Noisagul P, Fanhchaksai K, Sathitsamitphong L, Choed-Amphai C, Charoenkwan P, Chaiyawat P, Sangphukieo A, Natesirinilkul R.   +10 more
europepmc   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Conformal Growth of Stable 1T-Phase WS₂ by Alkali Metal-Halide-Assisted Chemical Vapor Deposition. [PDF]

Cryst Growth Des
Motta A, Serafini A, Targa P, Codegoni D, Grazianetti C, Martella C.   +5 more
europepmc   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Pushing the boundaries of virtual screening scale of combinatorial spaces with the V-SYNTHES approach. [PDF]

NPJ Drug Discov
Protopopov M, Semenenko O, Vasylchuk M, Sadybekov AV, Sadybekov AA, Horbatok K, Hrabovskyi O, Kapeliukha A, Nazarova A, Radchenko D, Katritch V, Tarkhanova O.   +11 more
europepmc   +1 more source

Test-based hybrid component mode synthesis. [PDF]

, 2018
openaire   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Effects of feeding high-moisture corn on performance, meat quality, and cecal microbiota of Jinling Yellow chickens. [PDF]

Front Vet Sci
Li T, Maimaitimin B, Song L, Abduli S, Liu Y, Wang Y, Aihemaiti N, Shao W, Yang L, Ren W.   +9 more
europepmc   +1 more source