Results 131 to 140 of about 2,013,324 (312)

¿Cómo llegar a un plan estratégico útil? Consejos prácticos antes de iniciar el proceso [PDF]

, 2014
Esta guía ofrece consejos prácticos para desarrollar un proceso útil y para negociar con consultores externos y sugiere una metodología con pasos y secuencia a seguir para conducir una planificación ...
Martha Farmelo, Victoria Wigodzky
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Manipulador Robótico (Similar a brazo Humano) [PDF]

, 2008
El proyecto ROBOT-01 propone la construcción de un manipulador de 7 grados de libertad, aplicando las mas modernas técnicas de Simulación, diseño, CAD-3D, materiales compuestos, construcción de micro-mecánica, electrónica y software.
Castagnola, Juan Luis, Castillo, Jorge Eduardo, Martinez Moretti, María Paula, Misa, Alberto Fernando, Moyano, Javier Ignacio   +4 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Heredabilldad del índice de cosecha en trigo (Triticum aestivum L.) y su relación con tres componentes de rendimiento

Agronomía Colombiana, 1991
This research was carried out at the experiment station Obonuco, Pasto, from 1985 to 1987 with the purpose to determine heritability in broad sense, genetic gain, phenotypic correlations and genetic effects of the following characteristics: biological ...
Bolaños A. Antonio, Britto M. Rodrgio
doaj  

Using Remote Access for Sharing Experiences in a Machine Design Laboratory [PDF]

, 2013
A new Machine Design Laboratory at Marquette University has been created to foster student exploration and promote “hands-on” and “minds-on” learning. Laboratory experiments have been developed to give students practical experiences and expose them to ...
Marklin, Richard W., Jr., Nagurka, Mark L., Rodriguez Anton, Fernando   +2 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

LOS SISTEMAS DE INFORMACIÓN GEOGRÁFICA. UNA REVISIÓN

Revista de la Facultad de Ciencias Agropecuarias, 2018
Los Sistemas de Información Geográfica SIG, son una herramienta para el manejo de información geográfica, fundamental para trabajar hoy en día con todo tipo de información georreferenciada. Un SIG es un sistema compuesto por cinco componentes principales:
Dixon Fabián Flórez Delgado, Deisy Katherine Fernández García   +1 more
doaj