Results 201 to 210 of about 2,013,324 (312)

[Cognitive-Behavioral therapy for patients with disability associated with chronic pain: systematic review of clinical trials] [PDF]

Rev Fac Cien Med Univ Nac Cordoba
Granizo Lara L, Carvajal Granizo V, Reyes Izurieta Á.   +2 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Componente Arterial na Acupuntura

, 2017
A acupuntura pode ser definida como uma arte ancestral utilizada pelos chineses há milénios como forma de prevenção e terapêutica de múltiplas patologias, nomeadamente vasculares, nervosas, inflamatórias, musculares e síndromes dolorosos, entre muitas outras.
openaire   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Infraestructura urbana: componente cultural

, 2014
Arquitecto
openaire   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Actions on childhood voice in public schools: a scoping review. [PDF]

Codas
Sebastião LT, Zamberlan-Amorim NE, Zambon F, Ribeiro VV, Behlau M.   +4 more
europepmc   +1 more source

COMPONENTE DE SEGMENTAÇÃO VISUAL

, 2019
Segundo um estudo realizado no Centro Universitário UNISEB (Costa, Nakata, & Calsani, 2013), os consumidores estão cada vez mais exigentes. O valor a pagar pelo serviço/produto final deixou de ser um problema relevante, por isso, as estratégias para reter clientes são uma constante procura por parte dos gestores de negócio. O marketing de fidelização é
openaire   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Inicio temprano de la gripe estacional y actividad emergente del virus respiratorio sincitial: Consecuencias para los sistemas de salud. [PDF]

Rev Panam Salud Publica
Organización Panamericana de la Salud.
europepmc   +1 more source