Results 111 to 120 of about 5,737,097 (385)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Analytical Method Development Using Central Composite Design for Estimation of Lamotrigine in Lipid Nanoformulation [PDF]

open access: diamond, 2020
Puja K. Gangurde   +4 more
openalex   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Effect of solar radiation on the properties of aramid fibers and composites

open access: yesCailiao gongcheng, 2019
K49 and F-Ⅲ two kinds of different structure aramid fibers and their 5224A epoxy matrix composites were selected. The tension strength of single fiber, FTIR, XPS, DSC, SEM,mechanical and dielectrical properties was used to characterize the ...
LI Ya-feng   +4 more
doaj   +1 more source

Controlled intermittent interfacial bond concept for composite materials [PDF]

open access: yes, 1975
Concept will enhance fracture resistance of high-strength filamentary composite without degrading its tensile strength or elastic modulus. Concept provides more economical composite systems, tailored for specific applications, and composite materials ...
Atkins, A. G., Marston, T. U.
core   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Synthesis of PAN with adjustable molecular weight and low polydispersity index (PDI) value via reverse atom transfer radical polymerization

open access: yesDesigned Monomers and Polymers, 2019
The reverse atom transfer radical polymerization (RATRP) of acrylonitrile (AN) was carried out in N, N-dimethylformamide (DMF) with AIBN as initiator, FeCl3•6H2O/triphenylphosphine (PPh3) and FeCl3•6H2O/pentamethyldle-thylenetrlamlne (PMDETA) as ...
Shuang Li   +8 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Composite piston [PDF]

open access: yes, 1988
A composite piston structure is disclosed which provides a simple and reliable means for joining a carbon-carbon or ceramic piston cap with a metallic piston body. Attachment is achieved by means of a special geometry which compensates for differences in
Taylor, Allan H.
core   +1 more source

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