Results 111 to 120 of about 1,911,260 (299)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Visual imitation learning from one-shot demonstration for multi-step robot pick and place tasks
Scientific ReportsImitation learning provides an intuitive approach for robot programming by enabling robots to learn directly from human demonstrations. While recent visual imitation learning methods have shown promise, they often depend on large datasets, which limits ...
Shuang Lu +2 more
doaj +1 more source
, 2019 This study investigates the in-plane localised crushing responses of carbon fibre reinforced epoxy (CF/EP) composite sandwich panels under a semi-circular indenter subjected to both quasi-static and dynamic loadings.
Chen, Yuan +3 more
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Thermal and Mechanical Performance of 3-Phase Polymer Composite Panels for Structural Applications
International Journal of Polymer ScienceThe objective of this study is to establish a conceptual framework for fiber-reinforced polymer composite (FRPC) panels designed for structural purposes through the incorporation of a third phase (fillers).
Muhammad Zubair Jilani +5 more
doaj +1 more source
On construction of robust composite indices by linear aggregation [PDF]
In this paper we construct thirteen different types of composite indices by linear combination of indicator variables (with and without outliers/data corruption). Weights of different indicator variables are obtained by maximization of the sum of squared
Mishra, SK
core
A PROGRESSIVE DAMAGE APPROACH FOR COMPOSITE STRUCTURES UNDER FATIGUE LOADING CONDITIONS
, 2012 In this paper a fatigue damage propagation numerical model based on gradual material degradation rules and Hashin fatigue failure criteria is formulated, implemented in a finite element platform and then used to simulate the intra-laminar fatigue damage ...
Mozzillo G +2 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
LOWFLIP - Tailored snap-cure prepregs for novel composite production processes
, 2016 Publisher Copyright: © 2016, European Conference on Composite Materials, ECCM. All rights reserved.The goal of EU-funded project "LOWFLIP" (= low cost flexible integrated composite process) is the development of low cost manufacturing processes for ...
Meinhardt, Thomas +2 more
core +1 more source