Results 101 to 110 of about 440,872 (301)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
CeramicsIn order to prepare diamond composites with excellent mechanical properties under non-extreme conditions, in this study, a diamond–ceramic composite was successfully prepared via reactive spark plasma sintering using a diamond–Ti–Si powder mixture as the
Yunwei Shi +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Influence of excess diamine on properties of PMR polyimide resins and composites [PDF]
By varying the stoichiometry of the reactants in the preparation of PMR polyimide resin, changes occur in molecular weight distribution which influence the rheological properties and thus the processability of the resin, as well as the mechanical ...
Hurwitz, F. I.
core +1 more source
High temperature resistant polyimide from tetra ester, diamine, diester and N-arylnadimide [PDF]
, 1985 The invention described relates to improved polyimide resins which are noted for their high thermal and oxidative stability, high strength at elevated temperatures and which exhibit many other outstanding physical and chemical properties, especially ...
Pater, R. H.
core +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Processing of advanced Al/SiC particulate metal matrix composites under intensive shearing – A novel rheo process [PDF]
, 2008 Particulate Metal Matrix Composites (PMMCs) have attracted interest for application in numerous fields. The current processing methods often produce agglomerated particles in the ductile matrix and as a result these composites exhibit extremely low ...
Barekar, NS +5 more
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Study effect of active flux on mechanical properties of TIG welding process
Results in EngineeringThe mechanical properties of low carbon steel welded using TIG process are studied in relation with the active fluxes, silicon oxide (SiO₂), manganese oxide (MnO₂), and the composite of 50 % SiO₂ and 50 % MnO₂. The research aims to investigate the impact
Zainab Hussein Mohsein +2 more
doaj +1 more source
A New Heavy Tailed Class of Distributions Which Includes the Pareto
Risks, 2019 In this paper, a new heavy-tailed distribution, the mixture Pareto-loggamma distribution, derived through an exponential transformation of the generalized Lindley distribution is introduced.
Deepesh Bhati +2 more
doaj +1 more source