Results 101 to 110 of about 128,175 (304)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2011 The service life of industrial components is limited predominantly by chemical corrosion, mechanical failure or mechanical wear. In the aluminium high pressure die casting industry, liquid aluminium is extremely reactive with the constituents of H13 die ...
Salman, Asma Siddiq
core
Advances in Materials Science and Engineering, 2020 To expand the application range of modified asphalt and mixtures and effectively reduce the aggregation of nanomaterials in asphalt, nanocarbon/styrene butadiene styrene (SBS)/rubber powder composite-modified asphalt is proposed.
Wenhui Zhao +5 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Localised low velocity impact performance of short glass fibre reinforced polyamide 66 oil pans [PDF]
, 2012 This thesis focuses on the mechanical properties of short glass fibre reinforced polyamide 66 material used in automotive composite structures, and its impact resistance under localised low velocity impact.
Mouti, Zakaria
core
Preparation and Properties of Composite Shape-Stabilized Phase Change Material for Asphalt Mixture
, 2011 Mixing the phase change material (PCM) into asphalt mixture could change the thermo physical properties of asphalt mixture. Asphalt mixture with PCM can remain in the ideal working temperature range for a relatively long time.
Da Long Wang +3 more
core +1 more source
Research on Preparation Technology of Recycled Building Decoration Materials
Chemical Engineering Transactions, 2017 In the present study, mechanical and physical properties were studied about the composite which was hot pressed by different kinds of modified phenol resin, then, one modified way was decided.
Xiaoxia Ye
doaj +1 more source
Bakery properties of composite mixtures of wheat and spelt flour
Новые технологии, 2018 Baking properties of the composite mixtures of flour (wheatand spelt) have been assessed. It ‘s shown that the introduction of spelt flour into the mixture leads to an increase in the activity of amylolytic enzymes. A decrease in the mass fraction of raw gluten in all samples of dough with the introduction of selt flour is observed.
N. S. Sanzharovskaya +4 more
openaire +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source