Results 111 to 120 of about 128,175 (304)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Prediction of thermo-mechanical properties for compression moulded composites
, 1998 We present a method to determine the thermo-mechanical properties of compression moulded composite parts. The flow-induced fibre orientation is first calculated by numerical simulation, and the resulting orientation state is used as input in a ...
Dupret, François +5 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Micromechanical response of fibre-reinforced materials using the boundary element technique
, 2003 The Boundary Element Method (BEM) and the Embedded Cell Approach (ECA) have been used to analyse the effects of constituent material properties and fibre spatial distribution on the localised behaviour of a transversely loaded, unidirectional fibre ...
Knight, MG, Wrobel, LC, Henshall, JL
core
MECHANICAL PROPERTIES OF RAMMED EARTH WITH RESPECT TO CLAY MIXTURE COMPOSITION
Acta Polytechnica, 2019 Unfired earth is a traditional building material, but it is less used than other building materials, such as concrete or steel. But the use of unfired earth is experiencing a renaissance. ammed earth is a type of unfired earth and is usually used for load bearing structures.
Tereza Plaček Otcovská +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
THE EFFECT OF TYPE ZEOLITE ON THE GAS TRANSPORT PROPERTIES OF POLYIMIDE-BASED MIXED MATRIX MEMBRANES [PDF]
, 2008 The permeation rates of O2, N2, CO2 and CH4 has been studied for polyimide-polyethersulfone (PI/PES) blends-zeolite mixed matrix membranes synthesized in our laboratory.
Ismail, Ahmad Fauzi +7 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
, 2018 The effects of the mixture of pig skin (PS) and coconut powder (CP) on the gelling and rheological properties of composite gel prepared with squid myofibrillar protein (MP) and lard were studied.
Shengnan Fu +4 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source