Results 51 to 60 of about 3,211,401 (356)

Radiotherapy Delivery in Deep Inspiration for Pediatric Patients—Final Results of the Phase II Feasibility Study TEDDI

open access: yesPediatric Blood &Cancer, EarlyView.
Abstract Introduction The TEDDI trial tested the feasibility and reproducibility of deep‐inspiration breath‐hold (DIBH) in pediatric patients referred for radiotherapy. This report presents final results, including patient‐reported outcomes (PRO) and dosimetric comparison of DIBH and free‐breathing (FB).
Daniella Elisabet Østergaard   +11 more
wiley   +1 more source

An Assessment of the Behaviour of Ceiling Beams of Different Structure

open access: yesApplied Sciences
The article focuses on floor composite beams used in buildings. Within the scope of the conducted analytical and numerical studies, the authors compared the typical solution—namely, the T-shaped reinforced concrete beam—with various types of composite ...
Katarzyna Ciesielczyk   +7 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Structural performance of composite beams: effects of continuity and slenderness ratio

open access: yesJournal of Engineering and Applied Science
An experimental study was conducted to investigate the performance of both simply supported and continuous steel beams acting compositely with reinforced concrete slabs using profiled steel sheeting and shear connectors.
Ahmed Safy   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Experimental Study of Ultra Shallow Floor Beams (USFB) with Perforated Steel Sections [PDF]

open access: yes, 2009
: In modern building construction design, floor spans are becoming longer. Hence, steel framed structures have become more competitive when compared with traditional reinforced concrete framed buildings. In order to minimise the structural section of the
D'Mello, C.   +2 more
core  

Partially connected composite beams [PDF]

open access: yesPAMM, 2006
AbstractAnalytical solutions to some boundary value problems for a steel‐concrete composite beam with deformable shear connectors in the elastic range are presented. The obtained results show that the distribution of slip on the bond interface between the concrete slab and the steel girder is not a monotone function, even in the case of uniform loading
Mieczysław Kuczma, Bożena Kuczma
openaire   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Experimental study on flexural behavior of the BFRC-concrete composite beams

open access: yesCase Studies in Construction Materials, 2021
Three specimens of composite beams were tested under a four-points bending test to study the effect of BFRC height on the flexural behavior of the composite beam. The numerical software MATLAB was used to numerically study the bending moment-curvature (M-
Zhiwen Zhang   +9 more
doaj   +1 more source

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