Results 91 to 100 of about 3,058,734 (312)

Load Capacities of Steel and Concrete Composite Bridge Deck Slab with Haunch

open access: yes, 2017
An innovative steel and concrete composite bridge deck slab using bent bars and epoxy as shear connectors was proposed. Four slab specimens with different types of concrete were fabricated and tested to study the load capacities of positive and negative ...
Xiaoqing Xu, Yuqing Liu
semanticscholar   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Case study of first all-GFRP pedestrian bridge in Taiwan

open access: yesCase Studies in Construction Materials, 2014
To forestall the severe deterioration of structures as a result of corrosion, the first all-FRP composite pedestrian bridge was built in Tainan, Taiwan.
Yeou-Fong Li   +3 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Study on Residual Load-Bearing Capacity of Composite Steel Truss Bridge Girders After Vehicle Fire

open access: yesBuildings
To investigate the residual load-bearing capacity of composite steel truss bridge girders after vehicle fire, a 100 m simple supported composite steel truss bridge girder was selected as the research object, and a typical oil tanker fire was taken as the
Shichao Wang   +3 more
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

open access: yesAging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef   +2 more
wiley   +1 more source

The Effect of Environment on Timber-concrete Composite Bridge Deck

open access: yes, 2016
In the field of timber bridges progressive static structural solution is if the timber bearing members of the bridge deck are combined with concrete layer applying a shear connection to receive their composite action. The composite timber-concrete bridge
V. Bajzecerová, J. Kanócz
semanticscholar   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy