Results 71 to 80 of about 54,041 (265)

Structural Design and Mechanical Behavior Investigation of Steel–Concrete Composite Decks of Narrow-Width Steel Box Composite Bridge

open access: yesBuildings
Steel–concrete composite decks are commonly employed in narrow-width steel box composite girder bridges to augment their lateral spanning capabilities, while the concurrent omission of longitudinal stiffeners leads to a substantial reduction in the ...
Yunteng Chen   +7 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

A Dynamic Interaction Analysis of a Straddle Monorail Train and Steel–Concrete Composite Bridge

open access: yesBuildings
Train–bridge dynamic interaction analysis is critical for the dynamic design of bridges and the safety and comfort assessment of trains. This study introduces a train–bridge dynamic model of a straddle monorail train and a steel–concrete composite track ...
Zhiyong Yao, Zongchao Liu, Zilin Zhong
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Improvement on design analyses of composite steel-concrete bridges using elaborate finite element methods [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2010
In this paper, three-dimensional finite element analysis of composite steel-concrete bridges is performed to simulate theactual bridge behavior. The accuracy of the model is verified against the results acquired from a field test.
Jaturong Sanguanmanasak   +2 more
doaj  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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